Mayer, Brian P. published the artcileStatistical analysis of the chemical attribution signatures of 3-methylfentanyl and its methods of production, Category: piperidines, the main research area is forensic chem attribution signature methylfentanyl; 3-methylfentanyl; Chemical attribution signature; Chemical forensics; Forensic attribution; Machine learning; Opioid.
Chem. attribution of the origin of an illegal drug is a key component of forensic efforts aimed at combating illicit and clandestine manufacture of drugs and pharmaceuticals. The results of these studies yield detailed information on synthesis byproducts, reagents, and precursors that can be used to identify the method of manufacture In the present work, chem. attribution signatures (CAS) associated with the synthesis of the analgesic 3-methylfentanyl, N-(3-methyl-1-phenethylpiperidin-4-yl)-N-phenylpropanamide, were investigated. Eighteen crude samples from six synthesis methods were generated, the anal. of which was used to identify signatures (i.e., chem. compounds) that were important in the discrimination of synthetic route. These methods were carefully selected to minimize the use of scheduled precursors, complicated laboratory equipment, number of steps, and extreme reaction conditions. Using gas and liquid chromatogs. combined with time-of-flight mass spectrometry (GC-QTOF and LC-QTOF) over 160 distinct species were monitored. Anal. of this combined data set was performed using modern machine learning techniques capable of reducing the size of the data set, prioritizing key chem. attribution signatures, and identifying the method of production for blindly synthesized 3-methylfentanyl materials.
Talanta published new progress about Drugs of abuse. 5773-58-0 belongs to class piperidines, name is 3-Methylpiperidin-4-one, and the molecular formula is C6H11NO, Category: piperidines.
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem