Dou, Zhe published the artcileKinetic resolution of nearly sym. 3-cyclohexene-1-carboxylate esters using a bacterial carboxylesterase identified by genome mining, Synthetic Route of 1690-74-0, the main research area is kinetic resolution carboxyesterase enzymic hydrolysis.
A new bacterial carboxylesterase (CarEst3) was identified by genome mining and found to efficiently hydrolyze racemic Me 3-cyclohexene-1-carboxylate (rac-CHCM) with a nearly sym. structure for the synthesis of (S)-CHCM. CarEst3 displayed a high substrate tolerance and a stable catalytic performance. The enantioselective hydrolysis of 4.0 M (560 g·L-1) rac-CHCM was accomplished, yielding (S)-CHCM with a >99% ee, a substrate to catalyst ratio of 1400 g·g-1, and a space-time yield of 538 g·L-1·d-1.
Organic Letters published new progress about Enantioselective biochemical synthesis. 1690-74-0 belongs to class piperidines, name is Methyl 1-methylpiperidine-2-carboxylate, and the molecular formula is C8H15NO2, Synthetic Route of 1690-74-0.
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem