Zheng, Changsheng’s team published research in Journal of Combinatorial Chemistry in 2002-02-28 | CAS: 158922-07-7

Journal of Combinatorial Chemistry published new progress about Primary amines Role: RCT (Reactant), RACT (Reactant or Reagent). 158922-07-7 belongs to class piperidines, name is 1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-3-carboxylic acid, and the molecular formula is C21H21NO4, Product Details of C21H21NO4.

Zheng, Changsheng published the artcileA General Method for the Solid-Phase Synthesis of Unsymmetrical Tri- and Tetrasubstituted Ureas, Product Details of C21H21NO4, the main research area is urea unsym solid phase preparation.

A general method for the preparation of unsym. di-, tri-, and tetrasubstituted ureas on polymer supports is presented. Polymer-bound primary and secondary amines react with imidazolium salts (urea donors), which are generated from the reaction of N,N’-carbonyldiimidazole with primary and secondary amines followed by alkylation with MeI to give tri- and tetrasubstituted ureas in excellent yields (76-98%) and purities (80-99%).

Journal of Combinatorial Chemistry published new progress about Primary amines Role: RCT (Reactant), RACT (Reactant or Reagent). 158922-07-7 belongs to class piperidines, name is 1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-3-carboxylic acid, and the molecular formula is C21H21NO4, Product Details of C21H21NO4.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem