Kulkarni, Santosh S. published the artcileDesign and synthesis of noncompetitive metabotropic glutamate receptor subtype 5 antagonists, Recommanded Product: 1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-3-carboxylic acid, the main research area is metabotropic glutamate receptor subtype 5 antagonist aroylaminopyridine aroylaminothiazole preparation.
A series of diaryl amides was designed and synthesized as novel nonethynyl mGluR5 antagonists. The systematic variation of the pharmacophoric groups led to the identification of a lead compound that demonstrated micromolar affinity for the mGluR5. Further optimization resulted in compounds with improved binding affinities and antagonist profiles, in vitro.
Bioorganic & Medicinal Chemistry Letters published new progress about. 158922-07-7 belongs to class piperidines, name is 1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-3-carboxylic acid, and the molecular formula is C21H21NO4, Recommanded Product: 1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-3-carboxylic acid.
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem