On May 1, 2019, Verheyen, Thomas; van Turnhout, Lars; Vandavasi, Jaya Kishore; Isbrandt, Eric S.; De Borggraeve, Wim M.; Newman, Stephen G. published an article.SDS of cas: 39512-49-7 The title of the article was Ketone Synthesis by a Nickel-Catalyzed Dehydrogenative Cross-Coupling of Primary Alcohols. And the article contained the following:
In the presence of Ni(cod)2 or Ni(OTf)2 and Triphos [MeC(CH2PPh2)3], aryl triflates underwent chemoselective dehydrogenative coupling reactions with primary alkyl and benzylic alcs. using acetone as a hydrogen acceptor to yield ketones. Nonracemic 2-methyl-1-butanol underwent cross-coupling to yield a nonracemic alkyl aryl ketone in 91:9 er. This oxidative transformation is proposed to occur by generation of aldehydes from primary alcs. in situ by either hydrogen transfer oxidation or (pseudo)dehalogenation pathways followed by Ni-catalyzed carbonyl-Heck reaction to form the ketone product. The experimental process involved the reaction of 4-(4-Chlorophenyl)piperidin-4-ol(cas: 39512-49-7).SDS of cas: 39512-49-7
The Article related to aryl ketone chemoselective preparation, nickel catalyst chemoselective dehydrogenative coupling aryl triflate primary alc, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.SDS of cas: 39512-49-7
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem