On April 3, 2020, Min, Qing-Qiang; Yang, Jia-Wen; Pang, Meng-Juan; Ao, Gui-Zhen; Liu, Feng published an article.Electric Literature of 39512-49-7 The title of the article was Copper-Catalyzed Remote C(sp3)-H Amination of Carboxamides. And the article contained the following:
Here we report a method for the site-selective intermol. C(sp3)-H amination of carboxamides by merging transition-metal catalysis and the hydrogen atom transfer strategy. The reaction proceeds through a sequence of favorable single-electron transfer, 1,5-hydrogen atom transfer, and C-N cross-coupling steps, thus allowing access to a series of desired products. This reaction could accommodate a wide diversity of nitrogen nucleophiles as well as demonstrate excellent chemoselectivity and functional group compatibility. The experimental process involved the reaction of 4-(4-Chlorophenyl)piperidin-4-ol(cas: 39512-49-7).Electric Literature of 39512-49-7
The Article related to intermol amination carboxamide metal catalysis hydrogen atom transfer, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Electric Literature of 39512-49-7
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem