Avery, E. E.’s team published research in Journal of Molecular Catalysis in 1989 | CAS: 1690-72-8

Methyl 1-methylpiperidine-3-carboxylate(cas: 1690-72-8) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Reference of Methyl 1-methylpiperidine-3-carboxylate

Avery, E. E.; Baevsky, M. F.; Braswell, S. J.; Duffus, C. W.; Evans, G. O. II; Rocha, D. K.; Wynne, R. A. published their research in Journal of Molecular Catalysis on August 1 ,1989. The article was titled 《Palladium phosphine-catalyzed hydroesterifications of unsaturated nitrogen heterocycles》.Reference of Methyl 1-methylpiperidine-3-carboxylate The article contains the following contents:

Pd(PPh3)2Cl2-catalyzed hydroesterification of HCl salts of 1,2,3,6-tetrahydropyridine derivatives gave 37-95% conversion to mixtures of isomeric Me esters. E.g., treatment of N-carbethoxynortropidine with CO-MeOH in MeCOEt containing Pd(PPh3)2Cl2 gave 95% conversion to mainly 3- and 4-(carbomethoxy)isomers I and II, resp., in 1:1.5 ratio. The experimental part of the paper was very detailed, including the reaction process of Methyl 1-methylpiperidine-3-carboxylate(cas: 1690-72-8Reference of Methyl 1-methylpiperidine-3-carboxylate)

Methyl 1-methylpiperidine-3-carboxylate(cas: 1690-72-8) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Reference of Methyl 1-methylpiperidine-3-carboxylate

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem