In 2022,Tao, Maoling; Wang, An-Jun; Guo, Peng; Li, Weipiao; Zhao, Liang; Tong, Jie; Wang, Haoyang; Yu, Yanbo; He, Chun-Yang published an article in Advanced Synthesis & Catalysis. The title of the article was 《Visible-Light-Induced Regioselective Deaminative Alkylation of Coumarins via Photoredox Catalysis》.Synthetic Route of C10H20N2O2 The author mentioned the following in the article:
A site-selective photocatalytic deaminative alkylation of coumarins utilizing pyridinium-activated aliphatic primary amines as alkylation reagents were reported. The protocol was highlighted by its mild reaction conditions, operational simplicity and broad functional group compatibility. Moreover, this strategy enabled late-stage modification of some pharmaceuticals and natural products, thus providing an appealing approach to valuable mols. in medicinal chem. After reading the article, we found that the author used tert-Butyl 4-aminopiperidine-1-carboxylate(cas: 87120-72-7Synthetic Route of C10H20N2O2)
tert-Butyl 4-aminopiperidine-1-carboxylate(cas: 87120-72-7) belongs to anime. Milder oxidation, using reagents such as NaOCl, can remove four hydrogen atoms from primary amines of the type RCH2NH2 to form nitriles (R―C≡N), and oxidation with reagents such as MnO2 can remove two hydrogen atoms from secondary amines (R2CH―NHR′) to form imines (R2C=NR′). Tertiary amines can be oxidized to enamines (R2C=CHNR2) by a variety of reagents.Synthetic Route of C10H20N2O2
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem