In 2017,Barberis, Claude; Moorcroft, Neil; Pribish, James; Tserlin, Elina; Gross, Alexandre; Czekaj, Mark; Barrague, Matthieu; Erdman, Paul; Majid, Tahir; Batchelor, Joseph; Levit, Mikhail; Hebert, Andrew; Shen, Liduo; Moreno-Mazza, Sandra; Wang, Anlai published 《Discovery of N-substituted 7-azaindoles as Pan-PIM kinase inhibitors – Lead series identification – Part II》.Bioorganic & Medicinal Chemistry Letters published the findings.Application In Synthesis of 2-(Piperidin-4-yl)ethanol The information in the text is summarized as follows:
N-Substituted azaindoles have been discovered as pan-PIM kinase inhibitors. Initial SAR, early ADME and PK/PD data of a series of compounds is described and led to the identification of promising pan-PIM inhibitors which validated the interest in the 7-azaindole scaffold and led us to pursue the identification of a clin. candidate. After reading the article, we found that the author used 2-(Piperidin-4-yl)ethanol(cas: 622-26-4Application In Synthesis of 2-(Piperidin-4-yl)ethanol)
2-(Piperidin-4-yl)ethanol(cas: 622-26-4) can be used to synthese ursolic acid derivatives, spiroimidazolidinone NPC1L1 inhibitors, neurokinin-2 receptor antagonists, antagonists for inhibition of platelet aggregation.Application In Synthesis of 2-(Piperidin-4-yl)ethanol
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem