Recommanded Product: 1-Methyl-4-piperidoneIn 2021 ,《Synthesis, Biological Evaluation, and Molecular Docking Studies of Some Spiro-5-Cyanopyrimidine Derivatives》 was published in Russian Journal of Bioorganic Chemistry. The article was written by Goda Pankaja Kumar; Sekhar, Thuraka; Thriveni, Pinnu; Venkateswarlu, Annavarapu; Peddanna, Kotha; Reddy, Peduri Suresh; Krishna, Mypati Hari; Sreelatha, Tumma. The article contains the following contents:
A simple, convenient, environmentally benign method has been developed for the synthesis of spiro-5-cyanopyrimidines by multi-component condensation of cyclic ketones, malononitrile and urea/thiourea using potassium carbonate in aqueous medium. The simple work-up procedure and good yield in short time are important features of this protocol. The synthesized compounds were tested for antibacterial activity against Gram pos. and Gram neg. bacteria and some of the tested compounds were found to have good antibacterial activities. Furthermore, docking study has been performed against enzyme of bacteria that showed good binding interactions. In the experiment, the researchers used 1-Methyl-4-piperidone(cas: 1445-73-4Recommanded Product: 1-Methyl-4-piperidone)
1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Recommanded Product: 1-Methyl-4-piperidone
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem