With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.309956-78-3,(R)-tert-Butyl piperidin-3-ylcarbamate,as a common compound, the synthetic route is as follows.

2) A mixture of 13.8 g (50 mmol) of 6-chloro-1- (2-isocyaninyl) -3-methylpyrimidine-2,4- (1H, 3H) -dione(R) -3-tert-butyloxycarbonylaminopiperidine (11.0 g, 55 mmol)Potassium carbonate 17.3 g (125 mmol) was mixed in DMF at 65 C,After the reaction,add water,Then extracted with dichloromethane,concentrate,N-hexane washing,(R) -tert-butyl-1- (3- (2-isocyaninyl) -1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidine- Yl) piperidin-3-ylcarbamate (21.6 g)The yield was 98.2%Purity 99.20%., 309956-78-3

The synthetic route of 309956-78-3 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Qingdao Chenda Biological Technology Co., Ltd.; Chen, Linghao; (8 pag.)CN105837557; (2016); A;,
Piperidine – Wikipedia
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