With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.216854-23-8,(S)-tert-Butyl piperidin-3-ylcarbamate,as a common compound, the synthetic route is as follows.

216854-23-8, To a solution of l-chloro-7-methoxyisoquinoline-6-carbonitrile (218 mg) in DIPEA (4.0 mL) was added compound 1 (300 mg). The mixture was stirred at 120 C for 8 h. The title compound 2 was obtained as a yellow solid (170 mg, yield 45%) after standard work up procedure.

As the paragraph descriping shows that 216854-23-8 is playing an increasingly important role.

Reference£º
Patent; SYNBLIA THERAPEUTICS, INC.; XIE, Yinong; BABISS, Lee, E.; (89 pag.)WO2019/89422; (2019); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem