In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 120014-07-5, name is 2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one, introducing its new discovery. Quality Control of: 2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
The invention discloses a method for the preparation of donepezil hydrochloride, the 3-chloro-1 – (3,4-dimethoxyphenyl) propan-1-one (II) and N-benzyl-4-piperidyl base formaldehyde (III) the Lewis acid ionic liquid catalyst reaction under the conditions of, one-pot synthesis to make 1-benzyl-4 – (5,6 dimethoxy-1-indan-2-methylene)-piperidine (IV), and then passes through the reduction, to a (I) donepezil hydrochloride salt. The invention has the advantages of simple process, low production cost, environment-friendly, is suitable for industrial production. (by machine translation)
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 120014-07-5 is helpful to your research. Quality Control of: 2-((1-Benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
Reference：
Piperidine – Wikipedia,
Piperidine | C5H23886N – PubChem