Day: December 30, 2022

Morpholinosulfur Trifluoride (Morph-DAST)-Mediated Rearrangement in the Fluorination of Cyclic α,α-Dialkoxy Ketones toward 1,2-Dialkoxy-1,2-difluorinated Compounds was written by Surmont, Riccardo;Verniest, Guido;De Groot, Alex;Thuring, Jan Willem;De Kimpe, Norbert. And the article was included in Advanced Synthesis & Catalysis in 2010.Related Products of 33439-27-9 This article mentions the following:

The deoxofluorination of cyclic α,α-dialkoxy ketones with morpholinosulfur trifluoride gave title compounds, e.g. I (Z = BocN, CH₂, O, etc.). The reaction proceeds via a 1,2-alkoxy migration leading to mixtures of cis- and trans-isomers. In the experiment, the researchers used many compounds, for example, 1-Tosylpiperidin-4-one (cas: 33439-27-9Related Products of 33439-27-9).

1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. The piperidine moiety constitutes an important building block for the synthesis of a variety of bioactive natural products, alkaloids and other drugs. The piperidine and polyhydroxylated indolizidine derivatives have shown to be promising α-glucosidase inhibitors. The former are analogs of DNJ with an improved α-glucosidase inhibitory profile than that of DNJ. Boisson et al.Related Products of 33439-27-9

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Improved synthesis and radiolabeling of [¹¹C]MP4A, a suitable ligand for the investigation of the cholinergic system using PET was written by Carpinelli, A.;Magni, F.;Cattaneo, A.;Matarrese, M.;Turolla, E.;Todde, S.;Bosso, N.;Galli Kienle, M.;Fazio, F.. And the article was included in Applied Radiation and Isotopes in 2006.Category: piperidines This article mentions the following:

An improved synthesis of the precursor acetic acid-piperidine-4-yl ester by acetylation of 4-hydroxypiperidine hydrochloride in anhydrous chloroform was developed. A procedure for fast evaluation and characterization of products originated by acetylation of the 4-piperidinol using LC-APCI/MS with an acetonitrile-water gradient method on a Merck Purosphere RP-18 column was also developed. The highly purified precursor allowed the production of [¹¹C]MP4A for PET studies of acetylcholine neurotransmission system. The tracer was produced with >98% radiochem. purity, with yields ranging 20-60% (decay-corrected) from EOB. In the experiment, the researchers used many compounds, for example, 1-(4-Hydroxypiperidin-1-yl)ethanone (cas: 4045-22-1Category: piperidines).

1-(4-Hydroxypiperidin-1-yl)ethanone (cas: 4045-22-1) belongs to piperidine derivatives. Piperidine and its derivatives have become increasingly popular in many synthetic schemes. Piperidine prefers a chair conformation, similar to cyclohexane. Unlike cyclohexane, piperidine has two distinguishable chair conformations: one with the N–H bond in an axial position, and the other in an equatorial position.Category: piperidines

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem