Month: October 2022

Long, Yangke; Huang, Yixuan; Wu, Huiyi; Shi, Xiaowen; Xiao, Ling published their research in Chemical Engineering Journal (Amsterdam, Netherlands) on August 1 ,2019. The article was titled 《Peroxymonosulfate activation for pollutants degradation by Fe-N-codoped carbonaceous catalyst: Structure-dependent performance and mechanism insight》.Quality Control of Triacetonamine The article contains the following contents:

In this study, Fe-N-codoped carbonaceous catalysts (Fe-N-C-x) with different structures including one-dimensional carbon nanotubes (1D CNTs) and two-dimensional porous carbon sheets (2D NC) to three-dimensional carbon nanotubes/porous carbon sheets composites (3D CNTs/NC) were systematically synthesized and applied as peroxymonosulfate (PMS) activators. It was found that the Fe-N-C-x catalysts exhibited structure-dependent catalytic performance, following the order of 2D NC > 3D CNTs/NC > 1D CNTs, and also substrate-dependent degradation performance that the reaction kinetics varied greatly for different organic pollutants. Benefiting from the unique structure characteristic and high d. of active sites, 2D Fe-N-C-1 showed far superior catalytic performance than the generally used carbocatalysts with negligible Fe leaching. Besides, various influential factors affecting the catalytic performance were systematically investigated. Fe-N-C-1 showed high catalytic efficiencies toward a broad spectrum of organic pollutants, and it was confirmed that both radical and non-radical degradation pathways existed during pollutants degradation The competitive radical quenching tests and ESR measurements verified that the superoxide anion radical (OA·-2) was the primary reactive oxidized species for degradation of p-chlorophenol (4-CP). The chronoamperometry anal. demonstrated that Fe-N-C-1 facilitated the electron transfer from 4-CP to PMS, resulting in the degradation of 4-CP through a non-radical mechanism. Our result not only reveals the structure-dependent PMS activation performance of transition-metal and nitrogen codoped carbocatalysts but also provides solid evidence that the defect-rich carbon materials with amorphous carbon and partial graphitic structure also favor the electron transfer mechanism. The experimental process involved the reaction of Triacetonamine(cas: 826-36-8Quality Control of Triacetonamine)

Triacetonamine(cas: 826-36-8) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Quality Control of Triacetonamine

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Wang, Yujiao; Wang, Li; Ma, Fang; You, Yongqiang published an article in Chemical Engineering Journal (Amsterdam, Netherlands). The title of the article was 《FeOx@graphitic carbon core-shell embedded in microporous N-doped biochar activated peroxydisulfate for removal of Bisphenol A: Multiple active sites induced non-radical/radical mechanism》.Name: Triacetonamine The author mentioned the following in the article:

The development of novel carbocatalysts with high activity and stability is important for the rapid degradation of emerging pollutants. Fe/N co-doped biochar (FeOx@GC-NBC) was innovatively synthesized with a pyrolytic carbonization method and then used as a functional peroxydisulfate (PDS) activator to degrade Bisphenol A (BPA). FeOx@GC-NBC with an optimized Fe/N ratio modification exhibited 23.16 and 8.65-fold great activity for BPA removal compared to pristine BC and N-doped BC, resp. Approx. 93% of total organic carbon (TOC) could be removed in the heterogeneous activation system. We attributed the excellent performance of FeOx@GC-NBC to the following attributes: i) a microporous carbon matrix with larger sp. surface area (1691.81 m2·g-1) was favorable for adsorption, exposure of catalyst active sites (e.g., Fe-Nx, Graphitic N) and electron-transfer; ii) the C-O-Fe bond and highly core-shell structure of graphitic nanosheets (FeOx@GC) enhanced the N retention ability and durability of the catalyst; iii) organics adsorption dominated by a “”pore-filling and π-π interaction”” mechanism effectively promoted BPA oxidation In acidic and neutral solutions, the radical oxidation (SO·-4and ·OH) processes were responsible for BPA decomposition In alk. solution, electron transfer, instead of 1O2 or a high-valent iron species, was the dominant pathway. This study proposes a simple and feasible strategy to synthesize the FeOx@GC-NBC catalyst, which provides insights into catalyst design and the internal active sites involved in the purification mechanism of refractory organics The experimental part of the paper was very detailed, including the reaction process of Triacetonamine(cas: 826-36-8Name: Triacetonamine)

Triacetonamine(cas: 826-36-8) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Name: Triacetonamine

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

The author of 《Photoredox-catalyzed synthesis of sulfones through deaminative insertion of sulfur dioxide》 were Wang, Xuefeng; Kuang, Yunyan; Ye, Shengqing; Wu, Jie. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Reference of tert-Butyl 4-aminopiperidine-1-carboxylate The author mentioned the following in the article:

Katritzky salts were used as the alkyl radical precursors with the insertion of sulfur dioxide under photoredox catalysis. This transformation first enables direct generation of various alkylsulfonyl radicals by photoinduced single electron reduction, leading to diverse dialkyl sulfones in good to excellent yields. A radical pathway was proposed under visible-light induced conditions with the insertion of sulfur dioxide. In the experiment, the researchers used tert-Butyl 4-aminopiperidine-1-carboxylate(cas: 87120-72-7Reference of tert-Butyl 4-aminopiperidine-1-carboxylate)

tert-Butyl 4-aminopiperidine-1-carboxylate(cas: 87120-72-7) belongs to anime. Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, such as RCOOH or RSO3H, by removal of ―OH, such as RC(=O)―, RS(O)2―, and so on). Reagents may be acid chlorides (RCOC1, RSO2C1), anhydrides ((RCO)2O), or even esters (RCOOR′); the products are amides of the corresponding acids.Reference of tert-Butyl 4-aminopiperidine-1-carboxylate

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Sharma, Jeet; Misra, S. K.; Kulshrestha, Vaibhav published an article in 2021. The article was titled 《Internally crosslinked poly(2,6-dimethyl-1,4-phenylene ether) based anion exchange membrane for recovery of different acids by diffusion dialysis》, and you may find the article in Chemical Engineering Journal (Amsterdam, Netherlands).Electric Literature of C6H11NO The information in the text is summarized as follows:

Acid recovery from acidic waste is a critical issue to be focused on nowadays. Chem. approaches for recovery are not com. viable and energy intensive to save the environment. Here, we report internally crosslinked poly (2,6-dimethyl-1,4-phenylene ether) (PPE) based anion exchange membranes (AEMs) for acid recovery by diffusion dialysis, prepared via quick grafting of N-methyl-4-piperidone using ultrasonication. The prepared AEMs are assessed for their physicochem. parameters and depicted water uptake (WU) and ion-exchange capacity (IEC) in the range 22.00%-31.00% and 0.64 meq/g-2.18 meq/g resp. for Cl-1, NO-3 and SO2-4 ions. AEMs were investigated for recovery of hydrochloric acid (HCl), nitric acid (HNO3) and sulfuric acid (H2SO4) from simulated effluent based on their proton diffusion coefficient (U+H), separation factor (S) and recovery efficiency. These membranes illustrated the proton diffusion coefficient as high as 0.065 m h-1 and enhanced separation factor values up to 132 at 27°C. Recovery performance for different acids is corroborated based on unique self-organized membrane structure, studied using AFM phase imaging and cumulative influence of bulk diffusion coefficient, ion-exchange capacity, and hydration radii of Cl-1, NO-3 and SO2-4 ions. The acid recovery efficiency illustrated the trend HCl > HNO3 > H2SO4. The hydrate (-OH) functionality with a non-overlapping set of lone pairs on oxygen enhances the proton mobility via Grotthuss mechanism inside the membrane matrix and provides a cradle-like pathway for high proton mobility. The results are pronounced for fabricated membranes compared to com. available standards for acid recovery via diffusion dialysis. In addition to this study using 1-Methyl-4-piperidone, there are many other studies that have used 1-Methyl-4-piperidone(cas: 1445-73-4Electric Literature of C6H11NO) was used in this study.

1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.Electric Literature of C6H11NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Application of 109384-19-2In 2021 ,《Development of autotaxin inhibitors: A series of tetrazole cinnamides》 was published in Bioorganic & Medicinal Chemistry Letters. The article was written by Thomson, Christopher G.; Le Grand, Darren; Dowling, Mark; Beattie, David; Elphick, Lucy; Faller, Michael; Freeman, Mark; Hardaker, Elizabeth; Head, Victoria; Hemmig, Rene; Hill, Johan; Lister, Andrew; Pascoe, David; Rieffel, Sebastien; Shrestha, Binesh; Steward, Oliver; Zink, Florence. The article contains the following contents:

A series of inhibitors of autotaxin (ATX) have been developed from a high throughput screening hit, 1a (I), which shows an alternative binding mode to known catalytic site inhibitors. Selectivity over the hERG channel and microsomal clearance were dependent on the lipophilicity of the compounds, and this was optimized by reduction of clogD while maintaining high affinity ATX inhibition. Compound 15a (II) shows good oral exposure, and concentration dependent inhibition of formation of LPA in vivo, as shown in pharmacokinetic-pharmacodynamic (PK/PD) experimentstert-Butyl 4-hydroxypiperidine-1-carboxylate(cas: 109384-19-2Application of 109384-19-2) was used in this study.

tert-Butyl 4-hydroxypiperidine-1-carboxylate(cas:109384-19-2) is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.Application of 109384-19-2

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Related Products of 826-36-8On September 15, 2020 ,《Activation of persulfate for tetracycline degradation using the catalyst regenerated from Fenton sludge containing heavy metal: Synergistic effect of Cu for catalysis》 was published in Chemical Engineering Journal (Amsterdam, Netherlands). The article was written by Shen, Minxian; Huang, Zhujian; Luo, Xuewen; Ma, Yujia; Chen, Chengyu; Chen, Xian; Cui, Lihua. The article contains the following contents:

Fenton reaction is widely used as a unique oxidation method for industrial wastewater treatment; however, it generates a massive amount of Fe sludge, which mostly contains other hazardous heavy metal wastes which can harm the environment and humans. This work proposed a sustainable method to eliminate side effects of the Fenton reaction and to transform Cu-containing Fenton sludge into an efficient catalyst for peroxymonosulfate (PMS) activation for tetracycline (TC) degradation The existence of Cu, which can increase sludge O2 vacancies, was attributed to the activation efficiency compared to Fe sludge with no Cu. X-ray diffraction and XPS results showed Fe is present as α-Fe2O3 and γ-Fe2O3; Cu mostly exists as Cu2+. Catalyst and PMS doses, pH, and recycling time effect on PMS reaction was illustrated. OH-, SO4- O2-, and 1O2 were the critical reactive oxygen species. TC decomposes into CO2 and water through six possible pathway processes with these free radicals. Given its sustainable treatment and high catalytic efficiency, dealing with Fe sludge which contains heavy metals serves as a modal practice for harmful wastewater treatment and can be popularized for broader applications. The experimental process involved the reaction of Triacetonamine(cas: 826-36-8Related Products of 826-36-8)

Triacetonamine(cas: 826-36-8) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Related Products of 826-36-8

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Recommanded Product: 826-36-8On September 1, 2020 ,《Defect-rich carbon based bimetallic oxides with abundant oxygen vacancies as highly active catalysts for enhanced 4-aminobenzoic acid ethyl ester (ABEE) degradation toward peroxymonosulfate activation》 was published in Chemical Engineering Journal (Amsterdam, Netherlands). The article was written by Huang, Zhiyan; Wu, Pingxiao; Liu, Juan; Yang, Shanshan; Chen, Meiqing; Li, Yihao; Niu, Wenchao; Ye, Quanyun. The article contains the following contents:

meeting severe environmental problems, highly efficient, environment-friendly, multiple reusable catalysts are demanding to develop. this work prepared C-based bimetallic oxides with O vacancies for peroxymonosulfate activation to degrade 4-aminobenzoic acid Et ester (ABEE). among different molar ratios of Fe2+ and Mn ions, Fe1Mn1-Fe NC had the optimum catalytic performance. ABEE degradation should have free radical and non-free radical pathways. all sulfate, hydroxyl, and superoxide radicals and singlet oxygen were responsible for efficient ABEE degradation and mineralization. lattice O was the main reactive site for ABEE degradation electron transport provided a good synergistic redox reaction between Fe and Mn and promoted lattice O release. a proposed pathway for ABEE degradation included electrophilic and radical addition, H-abstraction reaction, and diazotization. this work was expected to provide rational design of bimetallic materials with oxygen vacancies for in-situ environmental remediation. In the part of experimental materials, we found many familiar compounds, such as Triacetonamine(cas: 826-36-8Recommanded Product: 826-36-8)

Triacetonamine(cas: 826-36-8) is a member of piperidine. Piperidine is ubiquitous structural motif widely occurred in diverse synthetically and naturally occurring bioactive molecules. Piperidines are an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.Recommanded Product: 826-36-8

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Chaturvedula, Prasad V.; Pin, Sokhom; Tholady, George; Conway, Charlie M.; Macor, John E.; Dubowchik, Gene M. published an article in Bioorganic & Medicinal Chemistry Letters. The title of the article was 《Design and synthesis of potent antagonists containing rigid spirocyclic privileged structures for the CGRP receptor》.Related Products of 136624-42-5 The author mentioned the following in the article:

We report the synthesis of rigid spirocyclic systems as conformationally constrained variants of the Ala-Phe-NH2 dipeptide amide C-terminus of the calcitonin gene-related peptide (CGRP). CGRP receptor antagonists containing these moieties displayed potent affinity, functional antagonism and excellent oxidative stability. Structure-activity relationship studies demonstrated the relative importance of hydrogen bond donor/acceptor functionalities and the preferred orientation of an aromatic ring. Antagonists showed potent and full reversal of CGRP-induced dilation of ex vivo human intracranial arteries.4-Amino-1-benzylpiperidine-4-carbonitrile(cas: 136624-42-5Related Products of 136624-42-5) was used in this study.

4-Amino-1-benzylpiperidine-4-carbonitrile(cas: 136624-42-5) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Related Products of 136624-42-5

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Huang, Zhiyan; Wang, Tenglu; Shen, Minxian; Huang, Zhujian; Chong, Yunxiao; Cui, Lihua published their research in Chemical Engineering Journal (Amsterdam, Netherlands) on August 1 ,2019. The article was titled 《Coagulation treatment of swine wastewater by the method of in-situ forming layered double hydroxides and sludge recycling for preparation of biochar composite catalyst》.HPLC of Formula: 826-36-8 The article contains the following contents:

In order to achieve enhanced treatment of swine wastewater as well as resource recycle, in this work, we applied coagulation treatment on swine wastewater by adding Fe and Mg ions, MgFe layered double hydroxides (LDHs) was yielded during coagulation process and the coagulation sludge was recycled to prepare biochar composite catalyst. The removal rates of total phosphorus (TP) and COD (COD) by Mg-Fe coagulation could achieve 82.55% and 98.51%, which is higher than that by coagulation with individual Mg2+ or individual Fe3+. Finely dispersed MgFe-LDHs flocculation was formed during the coagulation process and was embedded within zoogloea, suspended particles, organic matters, etc. The obtained coagulation sludge was recycled to prepare biochar composite catalyst by oxygen-limited pyrolysis. Redox reaction of iron compounds and electron shuttles capacity of biochar in the catalyst could activate potassium peroxymonosulfate (PMS) to generate ·OH, ·OOH and 1O2, which was responsible for catalysis potential. The as-prepared biochar composite catalyst showed satisfactory catalytic degradation capacity on tylosin and rhodamine B (pH value varied from 3 to 10), and the maximum degradation rate achieved 92.2% for tylosin and 81.9% for rhodamine B (RhB). Coagulation treatment of swine wastewater and in-situ formed layered double hydroxides recycling was suitable in wastewater treatment and resource recycling, of which the degradation rates of RhB were above 83% after five cycling experiments In general, the combined process exhibits great potential for the deep treatment of swine wastewater and resource recycling for sludge. In the part of experimental materials, we found many familiar compounds, such as Triacetonamine(cas: 826-36-8HPLC of Formula: 826-36-8)

Triacetonamine(cas: 826-36-8) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.HPLC of Formula: 826-36-8

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Sun, Qianqian; Liu, Bin; Wang, Zhao; Feng, Lili; Zhao, Ruoxi; Dong, Shuming; Dong, Yushan; Zhong, Lei; Gai, Shili; Yang, Piaoping published their research in Chemical Engineering Journal (Amsterdam, Netherlands) on December 1 ,2021. The article was titled 《H2O2/O2 self-supplementing and GSH-depleting Ca2+ nanogenerator with hyperthermia-triggered, TME-responsive capacities for combination cancer therapy》.Application In Synthesis of Triacetonamine The article contains the following contents:

The tumor microenvironment (TME) is complex in composition and unique in nature, and is closely related to the growth, invasion and metastasis of tumor cells. Improving and remodeling the TME to return it to a normalized state can fundamentally disrupt the environment and/or nutrient supply on which tumor cells depend. To achieve this goal, based on the unique physicochem. properties and biol. effects of CaO2, we designed and constructed a Ca2+ nanogenerator (named as CaO2-Cu/ICG@PCM) that enables H2O2/O2 self-supplementation and GSH depletion. The 808 nm laser induces the heat generation of photosensitizer indocyanine green (ICG) to initiate a series of reactions, followed by the production of copper ions, H2O2, O2 and large amounts of Ca2+, which can eventually lead to the combined treatment of photodynamic therapy (PDT), chemodynamic therapy (CDT) and calcium overload. Addnl., the reaction process is accompanied by the generation of Ca(OH)2, which greatly improves the acidic environment of TME and effectively promotes the oxidation process of GSH by H2O2, achieving the purpose of remodeling TME. It is worth mentioning that a large amount of free Ca2+ accumulating in tumor cells can rapidly initiate the process of calcium overload and calcification, which can not only play a role in tumor suppression, but also assist CT imaging to detect the effect of treatment. Thus, CaO2-Cu/ICG@PCM could be a promising candidate for bioimaging and tumor therapy. In the experimental materials used by the author, we found Triacetonamine(cas: 826-36-8Application In Synthesis of Triacetonamine)

Triacetonamine(cas: 826-36-8) is a member of piperidine. Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Hence, continuous efforts have been made to develop convenient methods to prepare piperidine derivatives.Application In Synthesis of Triacetonamine

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem