Month: September 2022

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. It is a colorless liquid with an odor described as objectionable, and typical of amines. Formula: C11H19NO4.

Piticari, Amalia-Sofia;Antermite, Daniele;Higham, Joe I.;Moore, J. Harry;Webster, Matthew P.;Bull, James A. research published 《 Stereoselective Palladium-Catalyzed C(sp³)-H Mono-Arylation of Piperidines and Tetrahydropyrans with a C(4) Directing Group》, the research content is summarized as follows. A selective Pd-catalyzed C(3)-H cis-functionalization of piperidine and tetrahydropyran carboxylic acids is achieved using a C(4) aminoquinoline amide auxiliary. High mono- and cis-selectivity is attained by using mesityl carboxylic acid as an additive. Conditions are developed with significantly lower reaction temperatures (≤50°C) than other reported heterocycle C(sp³)-H functionalization reactions, which is facilitated by a DoE optimization. A one-pot C-H functionalization-epimerization procedure provides the trans-3,4-disubstituted isomers directly. Divergent aminoquinoline removal is accomplished with the installation of carboxylic acid, alc., amide and nitrile functional groups. Overall, fragment compounds suitable for screening are generated in 3-4 steps from readily-available heterocyclic carboxylic acids.

Formula: C11H19NO4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. It is a colorless liquid with an odor described as objectionable, and typical of amines. Safety of 4-Piperidinol.

Pipal, Robert W.;Stout, Kenneth T.;Musacchio, Patricia Z.;Ren, Sumei;Graham, Thomas J. A.;Verhoog, Stefan;Gantert, Liza;Lohith, Talakad G.;Schmitz, Alexander;Lee, Hsiaoju S.;Hesk, David;Hostetler, Eric D.;Davies, Ian W.;MacMillan, David W. C. research published 《 Metallaphotoredox aryl and alkyl radiomethylation for PET ligand discovery》, the research content is summarized as follows. Positron emission tomog. (PET) radioligands (radioactively labeled tracer compounds) are extremely useful for in vivo characterization of central nervous system drug candidates, neurodegenerative diseases and numerous oncol. targets¹. Both tritium and carbon-11 radioisotopologues are generally necessary for in vitro and in vivo characterization of radioligands², yet there exist few radiolabelling protocols for the synthesis of either, inhibiting the development of PET radioligands. The synthesis of such radioligands also needs to be very rapid owing to the short half-life of carbon-11. Here we report a versatile and rapid metallaphotoredox-catalyzed method for late-stage installation of both tritium and carbon-11 into the desired compounds via methylation of pharmaceutical precursors bearing aryl and alkyl bromides. Me groups are among the most prevalent structural elements found in bioactive mols., and so this synthetic approach simplifies the discovery of radioligands. To demonstrate the breadth of applicability of this technique, we perform rapid synthesis of 20 tritiated and 10 carbon-11-labeled complex pharmaceuticals and PET radioligands, including a one-step radiosynthesis of the clin. used compounds [¹¹C]UCB-J and [¹¹C]PHNO. We further outline the direct utility of this protocol for preclin. PET imaging and its translation to automated radiosynthesis for routine radiotracer production in human clin. imaging. We also demonstrate this protocol for the installation of other diverse and pharmaceutically useful isotopes, including carbon-14, carbon-13 and deuterium.

5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., Safety of 4-Piperidinol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Reference of 2403-88-5.

Peng, Wei;Liu, Jie;Li, Chenxu;Zong, Fuxing;Xu, Wensi;Zhang, Xing;Fang, Zhendong research published 《 A multipath peroxymonosulfate activation process over supported by magnetic CuO-Fe₃O₄ nanoparticles for efficient degradation of 4-chlorophenol》, the research content is summarized as follows. Heterogeneous catalysts with low cost, environmentally friendly, highly effective and ready separation from aqueous solution are highly desirable. Magnetic CuO-Fe₃O₄ nanoparticles, a type of non-toxic bimetallic transition metal oxide, is a promising heterogeneous catalyst for activation of peroxymonosulfate (PMS) to generate reactive oxygen species (ROS) that has not been previously investigated. In this study, the activation of PMS by CuO-Fe₃O₄ nanoparticles was evaluated using the degradation of 4-chlorophenol as a model reaction. Several critical factors such as pH, catalyst dosage and PMS concentration were investigated. CuO-Fe₃O₄/PMS system demonstrated a wide effective pH range to degrade 4-chlorophenol, namely 5.5 to 9.5. With the increase of the catalyst dosage, the degradation efficiency of 4-chlorophenol appeared to increase first and then decrease, that the inflection point was 0.5 g/L. Elevated PMS concentration obviously improved the decomposition of 4-chlorophenol; however, the plateau was reached when the PMS concentration was 8 mM. Further increase in PMS concentration would not significantly improve the removal efficiency. Through examining the effects of scavengers and ESR (ESR) analyses, CuO-Fe₃O₄ nanoparticles were proven to activate PMS through a non-radical and radical pathway to generate singlet oxygen, sulfate radicals and hydroxyl radicals.

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Reference of 2403-88-5

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst: C5H5N + 3 H2 → C5H10NH. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol. Category: piperidines.

Patel, Piyush A.;Bruun, Tanja;Ilina, Polina;Makkyla, Heidi;Lempinen, Antti;Yli-Kauhaluoma, Jari;Tammela, Paivi;Kiuru, Paula S. research published 《 Synthesis and Cytotoxicity Evaluation of Spirocyclic Bromotyrosine Clavatadine C Analogs》, the research content is summarized as follows. Marine-originated spirocyclic bromotyrosines are considered as promising scaffolds for new anticancer drugs. In a continuation of research to develop potent and more selective anticancer compounds, authors synthesized a library of 32 spirocyclic clavatadine analogs by replacing the agmatine, i.e., 4-(aminobutyl)guanidine, side chain with different substituents. These compounds were tested for cytotoxicity against skin cancer using the human melanoma cell line (A-375) and normal human skin fibroblast cell line (Hs27). The highest cytotoxicity against the A-375 cell line was observed for dichloro compound I (CC₅₀ 0.4 ± 0.3μM, selectivity index (SI) 2). The variation of selectivity ranged from SI 0.4 to reach 2.4 for the pyridin-2-yl derivative II and hydrazide analog of 2-picoline III. The structure-activity relationships of the compounds in respect to cytotoxicity and selectivity toward cancer cell lines are discussed.

Category: piperidines, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. HPLC of Formula: 84358-13-4.

Park, Sang-Hyun;Shin, Insu;Kim, Young-Hyun;Shin, Injae research published 《 Mitochondrial Cl^–-Selective Fluorescent Probe for Biological Applications》, the research content is summarized as follows. Herein the authors describe the development of the first mitochondrial Cl^–-selective fluorescent probe, Mito-MQAE(I), and its applications in biol. systems. Fluorescence of Mito-MQAE is insensitive to pH over the physiol. pH range and is quenched by Cl^– with a Stern-Volmer quenching constant of 201 M^-1 at pH 7.0. The results of cell studies using Mito-MQAE show that substances with the ability to disrupt mitochondrial membranes cause increases in the mitochondrial Cl^– concentration

HPLC of Formula: 84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Recommanded Product: 4-Piperidinol.

Ou Yang, Cheng-Hsin;Liu, Wan-Hsuan;Yang, Sheng;Chiang, Yao-Yu;Shie, Jiun-Jie research published 《 Copper-Mediated Synthesis of (E)-β-Aminoacrylonitriles from 1,2,3-Triazine and Secondary Amines》, the research content is summarized as follows. A simple protocol for the synthesis of (E)-β-aminoacrylonitriles RCH=CHCN (R = dimethylamino, piperidin-1-yl, imidazol-1-yl, etc.) via Cu(OAc)₂-mediated nucleophilic addition of secondary amines such as piperidine, dimethylamine, imidazole, etc. to 1,2,3-triazine and an aerobic oxidation reaction was described. The reactions, which were studied with a broad substrate scope, are effective with cyclic, heterocyclic, aliphatic, allylic, and benzylic amines as well as L-proline derivatives The reactions use catalytic Cu(OAc)₂ to promote 1,2,3-triazine addition with various secondary amines, followed by in situ loss of nitrogen and subsequent imine oxidation to generate the corresponding (E)-β-aminoacrylonitriles in good yields with excellent stereoselectivities. These copper(II)-mediated aerobic oxidation reactions proceed under mild reaction conditions by oxidation of the Cu(II) species using mol. oxygen to complete the cycle without the participation of ligand, base or chem. oxidant additives.

Recommanded Product: 4-Piperidinol, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Application of C11H19NO4.

Oh, Sangmi;Kwon, Do Yoon;Choi, Inhee;Kim, Young Mi;Lee, Ji Young;Ryu, Jiyoung;Jeong, Hangyeol;Kim, Myung Jin;Song, Rita research published 《 Identification of Piperidine-3-carboxamide Derivatives Inducing Senescence-like Phenotype with Antimelanoma Activities》, the research content is summarized as follows. This study evaluated the potential use of senescence-inducing small mols. in the treatment of melanoma. We screened com. available small-mol. libraries with high-throughput screening and high-content screening image-based technol. Our findings showed an initial hit with the embedded N-arylpiperidine-3-carboxamide scaffold induced senescence-like phenotypic changes in human melanoma A375 cells without serious cytotoxicity against normal cells. A focused library containing diversely modified analogs were constructed and examined to evaluate the structure-activity relationship of N-arylpiperidine-3-carboxamide derivatives starting from hit 1. This work identified a novel compound with remarkable antiproliferative activity in vitro and demonstrated the key structural moieties within.

84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., Application of C11H19NO4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Formula: C5H11NO.

Niu, Ben;Sachidanandan, Krishnakumar;Blackburn, Bryan G.;Cooke, Maria Victoria;Laulhe, Sebastien research published 《 Photoredox Polyfluoroarylation of Alkyl Halides via Halogen-Atom-Transfer》, the research content is summarized as follows. The first polyfluoroarylation of unactivated alkyl halides RX (R = n-nonyl, cyclohexyl, adamantan-1-yl, 1-[(thiophen-2-yl)carbonyl]piperidin-4-yl, etc.; X = I, Br) e.g., I via halogen-atom-transfer process was described. This method converts primary, secondary, and tertiary alkyl halides into the resp. polyfluoroaryl compounds e.g., 3-(perfluorophenyl)butyl 4-methoxybenzoate in good yields in the presence of amide, carbamate, ester, aromatic and sulfonamide moieties including derivatives of complex bioactive mols. Mechanistic work revealed that this transformation proceeds through an alkyl radical generated after a halogen-atom-transfer.

Formula: C5H11NO, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. It is a colorless liquid with an odor described as objectionable, and typical of amines. Related Products of 84358-13-4.

Nie, Fang-Yuan;Cai, Yi-Ping;Song, Qin-Hua research published 《 Visible Light-Driven Decarboxylative Alkylation of Aldehydes via Electron Donor-Acceptor Complexes of Active Esters》, the research content is summarized as follows. In this paper, authors have developed photocatalyst-free and visible light-driven decarboxylative alkylation of pyridinaldehydes. The photochem. reactions are initiated via photoinduced single electron transfer from triethylamine to N-hydroxyphthalimide esters in electron donor-acceptor complexes. This photochem. method can achieve to translate 15 pyridinaldehydes and 11 2-quinolinaldehydes to the corresponding ketones. Furthermore, this strategy can also achieve two other transformations, disulfanes to aryl sulfides and a styrene sulfone to the alkyl-substituted alkene.

84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., Related Products of 84358-13-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. This gave the compound its name. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Other examples are the fire ant toxin solenopsin, the nicotine analog anabasine of tree tobacco (Nicotiana glauca), lobeline of Indian tobacco. Recommanded Product: 4-Piperidinol.

Ni, Tingjunhong;Ding, Zichao;Xie, Fei;Hao, Yumeng;Bao, Junhe;Zhang, Jingxiang;Yu, Shichong;Jiang, Yuanying;Zhang, Dazhi research published 《 Design, Synthesis, and In Vitro and In Vivo Antifungal Activity of Novel Triazoles Containing Phenylethynyl Pyrazole Side Chains》, the research content is summarized as follows. A series of triazole derivatives containing phenylethynyl pyrazole moiety as side chain I (R = 4-fluorobenzylaminyl, 4-hydroxypiperidin-1-yl, morpholin-4-yl, etc.) and II (R¹ = F, Cl, CN, CF₃, OCF₃) were designed, synthesized, and most of them exhibited good in vitro antifungal activities. Especially, triazole derivatives I (R = (furan-2-ylmethyl)aminyl) and II (R¹ = CN) showed excellent in vitro activities against C. albicans (MIC = 0.125, 0.0625μg/mL), C. neoformans (MIC = 0.125, 0.0625μg/mL), and A. fumigatus (MIC = 8.0, 4.0μg/mL). Triazole derivatives II (R¹ = CN) also exerted superior activity to triazole derivatives I (R = (furan-2-ylmethyl)aminyl) and fluconazole in inhibiting hyphae growth of C. albicans and inhibiting drug-resistant strains of C. albicans, and it could reduce fungal burdens in mice kidney at a dosage of 1.0 mg/kg. An in vivo efficacy evaluation indicated that triazole derivatives II (R¹ = CN) could effectively protect mice models from C. albicans infection at doses of 0.5, 1.0, and 2.0 mg/kg. These results suggested that triazole derivatives II (R¹ = CN) deserves further investigation.

5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., Recommanded Product: 4-Piperidinol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem