Day: September 22, 2022

Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst: C5H5N + 3 H2 → C5H10NH. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol. Application of C9H19NO.

Tan, Chaoqun;Xu, Tianhui;He, Huan;Xu, Qinglong;Fang, Chao;Du, Erdeng;Deng, Jing;Chu, Wenhai research published 《 Bimetallic oxychloride as an efficient oxone activator: Radical and non-radical oxidation of non-steroidal anti-inflammatory drugs》, the research content is summarized as follows. A novel iron-cobalt mixed oxychloride (CoFeOCl) nanosheet, with a plane size in the ranges of 0.2-1.0 μm and a thickness of 30-40 nm, was manufactured firstly and employed as catalyst for peroxymonosulfate (PMS) activation. The CoFeOCl/PMS system exhibits excellent catalytic activity for non-steroidal anti-inflammatory drugs removal at buffered pH 5.5-8.5 with extremely low catalyst dosage (0.03 g/L). The mechanism of PMS activation by CoFeOCl indicated that ·OH and ¹O₂ played a key role at pH 5.5-7.0 and pH 8.5 resp., and O^–₂· was involved for all pHs. The cycle of Co²⁺-Co³⁺ and Fe²⁺-Fe³⁺ were answerable to ·OH and ¹O₂ generation. Furthermore, CoFeOCl/PMS pre-oxidation before chlorination engendered in a reduce in the concentration of total disinfection byproducts (DBPs) at pH 8.5. A feasible reaction pathway of DBPs formation was examined with d. functional theory (DFT) calculation The findings provide a new routine for effective PMS activation.

Application of C9H19NO, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. It is a colorless liquid with an odor described as objectionable, and typical of amines. Formula: C9H19NO.

Takajo, Tokuko;Kurihara, Yoshinori;Iwase, Kodai;Miyake, Daiki;Tsuchida, Kazunori;Anzai, Kazunori research published 《 Basic investigations of singlet oxygen detection systems with ESR for the measurement of singlet oxygen quenching activities》, the research content is summarized as follows. Singlet oxygen (¹O₂) is highly oxidative and exerts strong cytotoxic effects. We tried to establish the best combination of a singlet oxygen generation system and a detection method with ESR, for measurement of the quenching activities of various substances. The photosensitizing reaction of rose bengal or thermal decomposition of 4-methyl-1,4-etheno-2,3-benzodioxin-1(4H)-propanoic acid (endoperoxide, EP) was used for the generation of ¹O₂, and a sterically hindered secondary amine, 2,2,6,6-tetramethyl-4-piperidone (TEMPD) or 2,2,6,6-tetramethyl-4-piperidinol (TEMP-OH), was used as the ¹O₂ detection probe. These secondary amines were oxidized by ¹O₂ to form stable nitroxide radicals, which were detectable by ESR. TEMPD was found to be readily oxidized by air, causing large background signals in comparison with TEMP-OH. The ESR signal obtained by the irradiation of rose bengal with visible light in the presence of TEMP-OH consisted of two kinds of nitroxide radical overlapping. In contrast, only a single nitroxide signal was observed when TEMP-OH was reacted with ¹O₂ generated from EP. Therefore, the best combination should be EP as the ¹O₂ generator and TEMP-OH as the detection probe. When using this combination, we found that the concentrations of some organic solvents such as DMSO and acetonitrile should be kept constant for reliable quantification, because the concentrations of organic solvents affect the ESR signal intensity.

Formula: C9H19NO, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Application of C9H19NO.

Tahir, Mudassir Hussain;Irfan, Rana Muhammad;Cheng, Xingxing;Ahmad, Muhammad Sajjad;Jamil, Muhammad;Shah, Tanveer-Ul- Hassan;Karim, Abdul;Ashraf, Rizwan;Haroon, Muhammad research published 《 Mango peel as source of bioenergy, bio-based chemicals via pyrolysis, thermodynamics and evolved gas analyses》, the research content is summarized as follows. Waste biomass is one of the promising feedstocks for bioenergy generation in present era. The aim of present study is to demonstrate Mango peel as a source of bioenergy, bio-based chem. and phenols productions via pyrolysis, thermodn. and evolved gas analyses. Therefore, samples were characterized through thermogravimetric analyzer, Fourier transform IR spectrometry (FTIR) and pyrolysis-gas chromatog./mass spectrometry (Py-GC/MS). Pyrolysis experiments were carried out at different heating rates i.e. 10, 20 and 30 °Cmin^-1 and thermodn. parameters were calculated using different kinetic models. The apparent activation energy was found in range of 88 kJ mol^-1 to 304 kJ mol^-1 with all kinetic models. Evolved gaseous anal. was performed though out pyrolysis and between three temperature intervals for qual. and quant. anal. of pyrolytic compounds Similarly, effect of temperature and heating rate on pyrolytic compounds concentrations were also carried out. Release of several chems., aromatics compounds and high phenols concentration i.e. 21.01% via Py/GC-MS confirms its potential for bioenergy, bio-based chems. productions and anti-oxidant characteristics associated with phenolic compounds

Application of C9H19NO, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. It is a colorless liquid with an odor described as objectionable, and typical of amines. Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol.

Tadic, Djordje;Manasfi, Rayana;Bertrand, Marine;Sauvetre, Andres;Chiron, Serge research published 《 Use of Passive and Grab Sampling and High-Resolution Mass Spectrometry for Non-Targeted Analysis of Emerging Contaminants and Their Semi-Quantification in Water》, the research content is summarized as follows. Different groups of organic micropollutants including pharmaceuticals and pesticides have emerged in the environment in the last years, resulting in a rise in environmental and human health risks. In order to face up and evaluate these risks, there is an increasing need to assess their occurrence in the environment. Therefore, many studies in the past couple of decades were focused on the improvements in organic micropollutants′ extraction efficiency from the different environmental matrixes, as well as their mass spectrometry detection parameters and acquisition modes. This paper presents different sampling methodologies and high-resolution mass spectrometry-based non-target screening workflows for the identification of pharmaceuticals, pesticides, and their transformation products in different kinds of water (domestic wastewater and river water). Identification confidence was increased including retention time prediction in the workflow. The applied methodol., using a passive sampling technique, allowed for the identification of 85 and 47 contaminants in the wastewater effluent and river water, resp. Finally, contaminants′ prioritization was performed through semi-quantification in grab samples as a fundamental step for monitoring schemes.

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. COA of Formula: C9H19NO.

Sun, Jie;Shen, Chun-Hui;Guo, Jie;Guo, He;Yin, Yi-Fei;Xu, Xin-Jie;Fei, Zheng-Hao;Liu, Zong-Tang;Wen, Xiao-Ju research published 《 Highly efficient activation of peroxymonosulfate by Co₃O₄/Bi₂WO₆ p-n heterojunction composites for the degradation of ciprofloxacin under visible light irradiation》, the research content is summarized as follows. Photocatalytic technol. assisted via peroxymonosulfate (PMS) has good potential in water treatment. In this study, the Co₃O₄/Bi₂WO₆ composite was constructed via an in-situ calcination process and used to activate PMS for the degradation of ciprofloxacin (CIP) under visible light irradiation The obtained 5 wt% Co₃O₄/Bi₂WO₆(CBWO-2) can highly effectively remove 86.2% CIP within 5 min visible light irradiation in presence of PMS. The excellent degradation performance of Co₃O₄/Bi₂WO₆/PMS system can be attributed to the synergistic effect between p-n heterojunction and PMS activation. The conduction band and valence band deviation between Co₃O₄ and Bi₂WO₆ were calculated by XPS techniques. Besides, DFT calculations were performed to further confirm the internal structure between Co₃O₄ and Bi₂WO₆. This work not only provides an approach to fabricate heterostructures but also indicated that Co₃O₄/Bi₂WO₆/PMS/Vis system is a potential environment remediation alternative for the efficient removal of recalcitrant organic compounds from wastewaters.

COA of Formula: C9H19NO, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol.

Sun, Hongwei;He, Fei;Choi, Wonyong research published 《 Production of Reactive Oxygen Species by the Reaction of Periodate and Hydroxylamine for Rapid Removal of Organic Pollutants and Waterborne Bacteria》, the research content is summarized as follows. Periodate (PI, IO₄^–) can be activated by hydroxylamine (HA), resulting in rapid removal of organic pollutants (within seconds). While previous studies on PI-based advanced oxidation processes proposed iodate radical (^•IO₃) as the major reactive species, no evidence of ^•IO₃ production was observed in the present PI/HA system. Reactive oxygen species (ROS) including ^•OH, HO₂^•, and ¹O₂, are proposed to be the main oxidants of the PI/HA system, as supported by tests using scavengers, chem. probes, and spin-trapping ESR. To minimize the risk of toxic iodinated byproduct formation caused by reactive iodine species, e.g., HOI and I₂, the HA:PI molar ratio was optimized at 0.6 to achieve a stoichiometric conversion of IO₄^– to iodate (IO₃^–), a preferred non-toxic I species sink. The PI/HA system also efficiently inactivated Gram-pos. and Gram-neg. bacteria, producing ¹O₂ as the dominant disinfectant. The ROS production mechanism was also assessed and is discussed in detail. This work offers a simple, highly efficient option for PI activation and ROS production which may find useful applications where urgent, rapid toxic pollutant removal is needed.

Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. It is a colorless liquid with an odor described as objectionable, and typical of amines. Name: 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid.

Song, Heng;Cheng, Ran;Min, Qiao-Qiao;Zhang, Xingang research published 《 Decarboxylative and Deaminative Alkylation of Difluoroenoxysilanes via Photoredox Catalysis: A General Method for Site-Selective Synthesis of Difluoroalkylated Alkanes》, the research content is summarized as follows. A general method for site-selective difluoroalkylation of alkyl carboxylic redox esters with difluoroenoxysilanes through photoredox-catalyzed decarboxylative reaction has been developed. The reaction can also be extended to aliphatic amine derived pyridinium salts. This method has the advantages of high efficiency, mild reaction conditions, and broad substrate scope, including primary, secondary, and sterically hindered tertiaryl alkyl substrates, providing a general and practical route for applications in organic synthesis and pharmaceutical studies.

84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., Name: 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst: C5H5N + 3 H2 → C5H10NH. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol. Safety of 4-Piperidinol.

Shimazumi, Ryoma;Tanimoto, Riku;Kodama, Takuya;Tobisu, Mamoru research published 《 Palladium-Catalyzed Unimolecular Fragment Coupling of N-Allylamides via Elimination of Isocyanate》, the research content is summarized as follows. A new unimol. fragment coupling (UFC) reaction that involves the palladium-catalyzed elimination of an isocyanate fragment from an amide, with the formation of carbon-carbon and carbon-heteroatom bonds was reported. An organometallic intermediate that is relevant to the catalytic reaction was characterized by X-ray crystallog. This UFC reaction enables the late-stage transformation of an amide functionality, allowing amides to be used as a convertible directing or protecting group.

5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., Safety of 4-Piperidinol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. It is a colorless liquid with an odor described as objectionable, and typical of amines. SDS of cas: 2403-88-5.

Shigemitsu, Hajime;Tani, Youhei;Tamemoto, Tomoe;Mori, Tadashi;Li, Xinxi;Osakada, Yasuko;Fujitsuka, Mamoru;Kida, Toshiyuki research published 《 Aggregation-induced photocatalytic activity and efficient photocatalytic hydrogen evolution of amphiphilic rhodamines in water》, the research content is summarized as follows. The development of photocatalysts is an essential task for clean energy generation and establishing a sustainable society. This paper describes the aggregation-induced photocatalytic activity (AI-PCA) of amphiphilic rhodamines and photocatalytic functions of the supramol. assemblies. The supramol. assemblies consisting of amphiphilic rhodamines with octadecyl alkyl chains exhibited significant photocatalytic activity under visible light irradiation in water, while the corresponding monomeric rhodamines did not exhibit photocatalytic activity. The studies on the photocatalytic mechanism by spectroscopic and microscopic analyses clearly demonstrated the AI-PCA of the rhodamines. Moreover, the supramol. assemblies of the rhodamines exhibited excellent photocatalytic hydrogen evolution rates (up to 5.9 mmol g^-1 h^-1).

SDS of cas: 2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. It is a colorless liquid with an odor described as objectionable, and typical of amines. Application of C5H11NO.

Shi, Shuai;Qiu, Wenting;Miao, Pannan;Li, Ruining;Lin, Xianfeng;Sun, Zhankui research published 《 Three-component radical homo Mannich reaction》, the research content is summarized as follows. By employing a radical process, enolizable aldehydes were utilized as substrates in the three-component radical homo-Mannich reaction for the streamlined synthesis of γ-amino-carbonyl compounds. The electrophilic radicals were generated from thiols HSCHR¹C(O)R² (R¹ = H, Me; R² = Me, EtO, PhCH₂O, 1-adamantyl, Et₂N, etc.) via the desulfurization process facilitated by visible-light, and then added to the electron-rich double bonds of enamines, formed in-situ from aldehydes or ketones R³CH₂C(O)R⁴ [R³ = H, Et, MeSCH₂, Ph, PhCH₂, etc., R⁴ = H; R³ = H, R⁴ = Ph, 3-FC₆H₄, etc.; R³R⁴ = (CH₂)₅, CH₂CHPhCH₂CH₂, CH₂N(CH₂Ph)CH₂CH₂, etc.] and amines R⁵NHR⁶ [R⁵ = Me, R⁶ = H₂C:CHCH₂, PhCH₂, cyclohexyl, etc.; R⁵ = PhCH₂, R⁶ = PhCH₂, EtO₂CCH₂, etc.; R⁵R⁶ = (CH₂)₄, CHPh(CH₂)₃, etc.] to provide the products I in a single step. The broad scope, mild conditions, high functional group tolerance, and modularity of this metal-free approach for the synthesis of complex tertiary amine scaffolds will likely be of great utility to chemists in both academia and industry.

Application of C5H11NO, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem