Day: September 22, 2022

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Application of C11H19NO4.

Wang, Hao;Jung, Hoimin;Song, Fangfang;Zhu, Shiyang;Bai, Ziqian;Chen, Danye;He, Gang;Chang, Sukbok;Chen, Gong research published 《 Nitrene-mediated intermolecular N-N coupling for efficient synthesis of hydrazides》, the research content is summarized as follows. N-N linkages are found in many natural compounds and endow fascinating structural and functional properties. In comparison to the myriad methods for the construction of C-N bonds, chem. for N-N coupling, especially in an intermol. fashion, remains underdeveloped. Here, we report a nitrene-mediated intermol. N-N coupling of dioxazolones and arylamines under iridium or iron catalysis. These reactions offer a simple and efficient method for the synthesis of various hydrazides from readily available carboxylic acid and amine precursors. Although the Ir-catalyzed conditions usually give higher N-N coupling yield than the Fe-catalyzed conditions, the reactions of sterically more demanding dioxazolones derived from α-substituted carboxylic acids work much better under the Fe-catalyzed conditions. Mechanistic studies revealed that the nitrogen atom of Ir acyl nitrene intermediates has strong electrophilicity and can undergo nucleophilic attack with arylamines with the assistance of Cl···HN hydrogen bonding to form the N-N bond with high efficiency and chemoselectivity.

Application of C11H19NO4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Synthetic Route of 2403-88-5.

Wang, Da;Xu, Haodan;Ma, Jun;Lu, Xiaohui;Qi, Jingyao;Song, Shuang research published 《 Morphology Control Studies of MnTiO₃ Nanostructures with Exposed {0001} Facets as a High-Performance Catalyst for Water Purification》, the research content is summarized as follows. Novel single-crystal hexagonal MnTiO₃ nanosheets with exposed {0001} facets have been synthesized via a simple one-pot hydrothermal method using NaOH as a mineralizer and tetraethylammonium hydroxide (TEAH) as a morphol. controller. The intermediate morphologies of MnTiO₃ nanostructures such as nanoparticles, nanowires, nanorods, and nanodiscs are trapped kinetically by adjusting the synthesis conditions. This approach enables us to elucidate the growth mechanisms of MnTiO₃ nanosheets based on the tetraethylammonium cation adsorption abilities on different MnTiO₃ crystal facets combined with d. functional theory calculations Dissolution and recrystallization processes are involved during the MnTiO₃ crystallization The surface-controlled MnTiO₃ has been found to be effective as a catalyst for ozonation in the degradation of 4-chlorophenol (4-CP). Within typical exptl. conditions (catalyst dosage = 0.3 g L^-1, [4-CP]₀ = 50 mg L^-1, [O₃] = 20 mg L^-1, gas flow = 0.1 L min^-1, pH 6.8, and T = 293 K), the total organic carbon (TOC) removal efficiency of 4-CP in catalytic ozonation with well-structured MnTiO₃ (MnTiO₃-180-10 sample) was 76.3% after 60 min, compared with only 22.1 and 38.5% TOC removal in the absence of catalyst and with uncontrolled MnTiO₃ (MnTiO₃-no TEAH sample), resp. Benefiting from the high exposure percentage of {0001} facet, mixed-valences of manganese, surface hydroxyl groups, and the enrichment Lewis acid sites provided by Mn and Ti, the morphol.-controlled MnTiO₃ nanosheets can be applied as heterogeneous catalytic ozonation catalysts which exhibit excellent pollutant degradation We anticipate that MnTiO₃ can be a promising candidate material for the application in remediation of organic pollutants in water.

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Synthetic Route of 2403-88-5

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. This gave the compound its name. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Other examples are the fire ant toxin solenopsin, the nicotine analog anabasine of tree tobacco (Nicotiana glauca), lobeline of Indian tobacco. Electric Literature of 5382-16-1.

Wang, Chenyang;Azofra, Luis Miguel;Dam, Phong;Sebek, Michael;Steinfeldt, Norbert;Rabeah, Jabor;El-Sepelgy, Osama research published 《 Catalytic Desaturation of Aliphatic Amides and Imides Enabled by Excited-State Base-Metal Catalysis》, the research content is summarized as follows. A photoexcited base-metal-catalyzed selective desaturation of aliphatic amides and imides was reported. The reaction was catalyzed by a base-metal cobalt complex under visible-light irradiation This transformation could be efficiently processed at room temperature and enabled the synthesis of valuable cyclic and acyclic enamides and enimides from abundant chems. D. functional theory (DFT) anal., ESR (EPR) and UV-vis studies rationalized the discovered reactivity of the cobalt catalyst for the photochem. C(sp³)-H activation reaction. Finally, demonstrated the potential of process by scaling-up experiments using a continuous flow photoreactor.

Electric Literature of 5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Category: piperidines.

Wan, Wen-jing;Ruan, Jian-cheng;Tang, Yun;Zhou, Shao-dong;Qian, Chao;Chen, Xin-zhi research published 《 Improvement of 2,2,6,6-tetramethyl-4-piperidinamine synthesis via catalytic amination》, the research content is summarized as follows. 2,2,6,6-Tetramethylpiperidinamine as light stabilizer of hindered amines was synthesized via catalytic amination of 2,2,6,6-tetramethylpiperidone. Imine formation was promoted by adjusting reaction system pH, which facilitated the catalytic amination under mild condition. The selectivity of the product was increased. When studied under pH∼12.5, reaction temperature 60°C and pressure 2 MPa, the selectivity of TEMP was up to 95.2%. The result shows that pH=12.5 is the most favorable condition for the formation of TEMP.

Category: piperidines, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. It is a colorless liquid with an odor described as objectionable, and typical of amines. Quality Control of 84358-13-4.

Walczak, Maciej;Chryplewicz, Agnieszka;Olewinska, Sandra;Psurski, Mateusz;Winiarski, Lukasz;Torzyk, Karolina;Oleksyszyn, Jozef;Sienczyk, Marcin research published 《 Phosphonic Analogs of Alanine as Acylpeptide Hydrolase Inhibitors》, the research content is summarized as follows. Acylpeptide hydrolase is a serine protease, which, together with prolyl oligopeptidase, dipeptidyl peptidase IV and oligopeptidase B, belongs to the prolyl oligopeptidase family. Its primary function is associated with the removal of N-acetylated amino acid residues from proteins and peptides. Although the N-acylation occurs in 50-90% of eukaryotic proteins, the precise functions of this modification remains unclear. Recent findings have indicated that acylpeptide hydrolase participates in various events including oxidized proteins degradation, amyloid β-peptide cleavage, and response to DNA damage. Considering the protein degradation cycle cross-talk between acylpeptide hydrolase and proteasome, inhibition of the first enzyme resulted in down-regulation of the ubiquitin-proteasome system and induction of cancer cell apoptosis. Acylpeptide hydrolase has been proposed as an interesting target for the development of new potential anticancer agents. Here, we present the synthesis of simple derivatives of (1-aminoethyl)phosphonic acid diaryl esters, phosphonic analogs of alanine diversified at the N-terminus and ester rings, as inhibitors of acylpeptide hydrolase and discuss the ability of the title compounds to induce apoptosis of U937 and MV-4-11 tumor cell lines.

Quality Control of 84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Recommanded Product: 4-Piperidinol.

Voloshkin, Vladislav A.;Kotovshchikov, Yury N.;Latyshev, Gennadij V.;Lukashev, Nikolay V.;Beletskaya, Irina P. research published 《 Annulation-Triggered Denitrogenative Transformations of 2-(5-Iodo-1,2,3-triazolyl)benzoic Acids》, the research content is summarized as follows. The ability of [1,2,3]triazolobenzoxazinones I (R¹ = H, 7-Br, 9-Me; R² = n-Bu, Ph, cyclohexylmethyl, 3-methylbutyl) to act as a source of “hidden” diazo group was discovered. These diazo precursors can be easily prepared by the intramol. cyclization of 2-(5-iodo-1,2,3-triazolyl)benzoic acids II (R³ = H, 5-Br, 3-Me, etc.). The Cu-catalyzed capture of the hidden diazo group allows for further functionalization through the denitrogenative pathway. The transformations proceed via the formation of either diazoimine or diazoamide intermediates. Novel routes to various anthranilamides R³NHC(O)CH(R²)R⁴ (R³ = 4,5-dimethoxy-2-[(pyrrolidin-1-yl)carbonyl]benzen-1-yl, 2-[(morpholin-4-yl)carbonyl]benzen-1-yl, 4-bromo-2-[(pyrrolidin-1-yl)carbonyl]benzen-1-yl, etc.; R⁴ = pyrrolidin-1-yl, (5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl, morpholin-4-yl, etc.) as well as thiolated benzoxazinones III (R⁵ = 5-methyl-1,3,4-thiadiazol-2-yl, 1,3-benzoxazol-2-yl, 1-methyl-1H-1,2,3,4-tetrazol-5-yl, etc.) were developed using the one-pot cyclization/diazo capture procedure.

5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., Recommanded Product: 4-Piperidinol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Recommanded Product: 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid.

Vimala, M.;Stella Mary, S.;Ramalakshmi, R.;Muthu, S.;Irfan, Ahmad research published 《 Computational prediction of polar and non-polar solvent effect on the electronic property of N-BOC- Piperidine-4-Carboxylic acid》, the research content is summarized as follows. Geometrical parameters and vibrational anal. of N-BOC-Piperidine-4-Carboxylic acid were computed using Hartree – Fock and D. functional theory with 6-311++G(d,p) basis set. Apparent change occurs in electronic property due to polar and non-polar solvents were investigated. The stabilization energy and mol. bonding interactions were calculated in NBO anal. Global descriptors and NLO parameters were predicted. Fukui functions, mol. electrostatic potential, reduced d. gradient isosurface, electron d. at bonding and antibonding were visualized. Total, partial and overall DOS spectrum were intricated to study the bonds overlapping interactions in the mol. Mol. docking was performed to reveal the protein interaction with BP4C.

Recommanded Product: 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. This gave the compound its name. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Other examples are the fire ant toxin solenopsin, the nicotine analog anabasine of tree tobacco (Nicotiana glauca), lobeline of Indian tobacco. Application In Synthesis of 2403-88-5.

van Iperen, Jolanda;van Keulen, Henk;Keune, Katrien;Abdulah, Kanaan;van Langh, Robert research published 《 Crystalline Deposits in New Display Cases at the Rijksmuseum: Characterisation and Origin》, the research content is summarized as follows. An unusual phenomenon occurred in new display cases at the Rijksmuseum four months after their installation in Apr. 2013. White deposits were visible on glass windows, silicone door gaskets, black structural adhesive seals, and on works of art. The works of art most affected by these deposits were bronze sculptures, wooden and waxed objects, tempera, and oil paintings. It was found that TMP-ol, which is part of the UV-light stabilizer Tinuvin-770, emitted from the structural adhesive Terostat-9220. Terostat-9220 was used in large quantities in the display cases to adhere glass windows to metal parts. The carboxylic acids derived from both construction materials used to build the cases and from conservation materials present on the exhibited works of art. The carboxylic acids involved were 2,4-dichlorobenzoic acid, formic acid, methacrylic acid, palmitic acid, and an unknown carboxylic acid, resp. emitted from peroxide-cured silicone gaskets, panels of medium-d. fiberboard (MDF), UV-adhesive, beeswax containing products, and from an unknown acidic conservation product or binding medium. The identification of the crystalline deposits was supported by their syntheses in the laboratory Since 2013, similar deposits have been observed in a number of museum collections worldwide. A treatment for preventing further growth of the deposits was developed and applied in the Rijksmuseum showcases.

Application In Synthesis of 2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Application In Synthesis of 5382-16-1.

Tu, Yongliang;Shi, Peng;Bolm, Carsten research published 《 2-Formyl Benzamides from an N-Phthalimidoyl Sulfoximine》, the research content is summarized as follows. Under mild conditions, an N-phthalimidoyl sulfoximine underwent aminolysis to provide a wide range of 2-formyl benzamides in good to high yields. An unprecedented variant of McFadyen-Stevens reaction explains the product formation. The applicability of the products as building blocks for nitriles and alkynes has been demonstrated.

5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., Application In Synthesis of 5382-16-1

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Formula: C11H19NO4.

Trammel, Grace L.;Kuniyil, Rositha;Crook, Phillip F.;Liu, Peng;Brown, M. Kevin research published 《 Nickel-Catalyzed Dearomative Arylboration of Indoles: Regioselective Synthesis of C2- and C3-Borylated Indolines》, the research content is summarized as follows. Indole dearomatization is an important strategy to access indolines: a motif present in a variety of natural products and biol. active mols. Herein, a method for transition-metal catalyzed regioselective dearomative arylboration of indoles to generate diverse indolines is presented. The method accomplishes intermol. dearomatization of simple indoles through a migratory insertion pathway on substrates that lack activating or directing groups on the C2- or C3-positions. Synthetically useful C2- and C3-borylated indolines can be accessed through a simple change in N-protecting group in high regio- and diastereoselectivities (up to >40:1 rr and >40:1 dr) from readily available starting materials. Addnl., the origin of regioselectivity was explored exptl. and computationally to uncover the remarkable interplay between carbonyl orientation of the N-protecting group on indole, electronics of the C2-C3 π-bond, and sterics. The method enabled the 1st enantioselective synthesis of (-)-azamedicarpin.

Formula: C11H19NO4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem