Day: September 21, 2022

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Recommanded Product: 4-Piperidinol.

Ou Yang, Cheng-Hsin;Liu, Wan-Hsuan;Yang, Sheng;Chiang, Yao-Yu;Shie, Jiun-Jie research published 《 Copper-Mediated Synthesis of (E)-β-Aminoacrylonitriles from 1,2,3-Triazine and Secondary Amines》, the research content is summarized as follows. A simple protocol for the synthesis of (E)-β-aminoacrylonitriles RCH=CHCN (R = dimethylamino, piperidin-1-yl, imidazol-1-yl, etc.) via Cu(OAc)₂-mediated nucleophilic addition of secondary amines such as piperidine, dimethylamine, imidazole, etc. to 1,2,3-triazine and an aerobic oxidation reaction was described. The reactions, which were studied with a broad substrate scope, are effective with cyclic, heterocyclic, aliphatic, allylic, and benzylic amines as well as L-proline derivatives The reactions use catalytic Cu(OAc)₂ to promote 1,2,3-triazine addition with various secondary amines, followed by in situ loss of nitrogen and subsequent imine oxidation to generate the corresponding (E)-β-aminoacrylonitriles in good yields with excellent stereoselectivities. These copper(II)-mediated aerobic oxidation reactions proceed under mild reaction conditions by oxidation of the Cu(II) species using mol. oxygen to complete the cycle without the participation of ligand, base or chem. oxidant additives.

Recommanded Product: 4-Piperidinol, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Application of C11H19NO4.

Oh, Sangmi;Kwon, Do Yoon;Choi, Inhee;Kim, Young Mi;Lee, Ji Young;Ryu, Jiyoung;Jeong, Hangyeol;Kim, Myung Jin;Song, Rita research published 《 Identification of Piperidine-3-carboxamide Derivatives Inducing Senescence-like Phenotype with Antimelanoma Activities》, the research content is summarized as follows. This study evaluated the potential use of senescence-inducing small mols. in the treatment of melanoma. We screened com. available small-mol. libraries with high-throughput screening and high-content screening image-based technol. Our findings showed an initial hit with the embedded N-arylpiperidine-3-carboxamide scaffold induced senescence-like phenotypic changes in human melanoma A375 cells without serious cytotoxicity against normal cells. A focused library containing diversely modified analogs were constructed and examined to evaluate the structure-activity relationship of N-arylpiperidine-3-carboxamide derivatives starting from hit 1. This work identified a novel compound with remarkable antiproliferative activity in vitro and demonstrated the key structural moieties within.

84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., Application of C11H19NO4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Formula: C5H11NO.

Niu, Ben;Sachidanandan, Krishnakumar;Blackburn, Bryan G.;Cooke, Maria Victoria;Laulhe, Sebastien research published 《 Photoredox Polyfluoroarylation of Alkyl Halides via Halogen-Atom-Transfer》, the research content is summarized as follows. The first polyfluoroarylation of unactivated alkyl halides RX (R = n-nonyl, cyclohexyl, adamantan-1-yl, 1-[(thiophen-2-yl)carbonyl]piperidin-4-yl, etc.; X = I, Br) e.g., I via halogen-atom-transfer process was described. This method converts primary, secondary, and tertiary alkyl halides into the resp. polyfluoroaryl compounds e.g., 3-(perfluorophenyl)butyl 4-methoxybenzoate in good yields in the presence of amide, carbamate, ester, aromatic and sulfonamide moieties including derivatives of complex bioactive mols. Mechanistic work revealed that this transformation proceeds through an alkyl radical generated after a halogen-atom-transfer.

Formula: C5H11NO, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. It is a colorless liquid with an odor described as objectionable, and typical of amines. Related Products of 84358-13-4.

Nie, Fang-Yuan;Cai, Yi-Ping;Song, Qin-Hua research published 《 Visible Light-Driven Decarboxylative Alkylation of Aldehydes via Electron Donor-Acceptor Complexes of Active Esters》, the research content is summarized as follows. In this paper, authors have developed photocatalyst-free and visible light-driven decarboxylative alkylation of pyridinaldehydes. The photochem. reactions are initiated via photoinduced single electron transfer from triethylamine to N-hydroxyphthalimide esters in electron donor-acceptor complexes. This photochem. method can achieve to translate 15 pyridinaldehydes and 11 2-quinolinaldehydes to the corresponding ketones. Furthermore, this strategy can also achieve two other transformations, disulfanes to aryl sulfides and a styrene sulfone to the alkyl-substituted alkene.

84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., Related Products of 84358-13-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. This gave the compound its name. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Other examples are the fire ant toxin solenopsin, the nicotine analog anabasine of tree tobacco (Nicotiana glauca), lobeline of Indian tobacco. Recommanded Product: 4-Piperidinol.

Ni, Tingjunhong;Ding, Zichao;Xie, Fei;Hao, Yumeng;Bao, Junhe;Zhang, Jingxiang;Yu, Shichong;Jiang, Yuanying;Zhang, Dazhi research published 《 Design, Synthesis, and In Vitro and In Vivo Antifungal Activity of Novel Triazoles Containing Phenylethynyl Pyrazole Side Chains》, the research content is summarized as follows. A series of triazole derivatives containing phenylethynyl pyrazole moiety as side chain I (R = 4-fluorobenzylaminyl, 4-hydroxypiperidin-1-yl, morpholin-4-yl, etc.) and II (R¹ = F, Cl, CN, CF₃, OCF₃) were designed, synthesized, and most of them exhibited good in vitro antifungal activities. Especially, triazole derivatives I (R = (furan-2-ylmethyl)aminyl) and II (R¹ = CN) showed excellent in vitro activities against C. albicans (MIC = 0.125, 0.0625μg/mL), C. neoformans (MIC = 0.125, 0.0625μg/mL), and A. fumigatus (MIC = 8.0, 4.0μg/mL). Triazole derivatives II (R¹ = CN) also exerted superior activity to triazole derivatives I (R = (furan-2-ylmethyl)aminyl) and fluconazole in inhibiting hyphae growth of C. albicans and inhibiting drug-resistant strains of C. albicans, and it could reduce fungal burdens in mice kidney at a dosage of 1.0 mg/kg. An in vivo efficacy evaluation indicated that triazole derivatives II (R¹ = CN) could effectively protect mice models from C. albicans infection at doses of 0.5, 1.0, and 2.0 mg/kg. These results suggested that triazole derivatives II (R¹ = CN) deserves further investigation.

5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., Recommanded Product: 4-Piperidinol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Related Products of 84358-13-4.

Nguyen, Vu T.;Haug, Graham C.;Nguyen, Viet D.;Vuong, Ngan T. H.;Karki, Guna B.;Arman, Hadi D.;Larionov, Oleg V. research published 《 Functional group divergence and the structural basis of acridine photocatalysis revealed by direct decarboxysulfonylation》, the research content is summarized as follows. The development of a photocatalytic system that for the first time enabled direct decarboxylative conversion of carboxylic acids to sulfones and sulfinates, as well as sulfonyl chlorides and fluorides in one step and in a multicomponent fashion. A mechanistic study prompted by the development of the new method revealed the key structural features of the acridine photocatalysts that facilitated the decarboxylative transformations and provided an informative and predictive multivariate linear regression model that quant. relates the structural features with the photocatalytic activity.

84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., Related Products of 84358-13-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. It is a colorless liquid with an odor described as objectionable, and typical of amines. Recommanded Product: 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid.

Nguyen, Vu T.;Haug, Graham C.;Nguyen, Viet D.;Vuong, Ngan T. H.;Arman, Hadi D.;Larionov, Oleg V. research published 《 Photocatalytic decarboxylative amidosulfonation enables direct transformation of carboxylic acids to sulfonamides》, the research content is summarized as follows. A visible light-induced, dual catalytic platform that for the first time allows for a one-step access to sulfonamides RS(O)₂R¹ (R = 4,4-dimethylcyclohexyl, heptadecyl, 4-oxo-4-phenylbutyl, etc.; R¹ = 2,3-dihydro-1H-indol-1-yl, (3,4,5-trimethylphenyl)aminyl, morpholin-4-yl, etc.) and sulfonyl azides R²S(O)₂N₃ (R² = 5-methoxy-5-oxopentyl, 4-(5-methylthiophen-2-yl)-4-oxobutyl, oxan-4-yl, etc.) directly from carboxylic acids R/R²COOH was reported. The broad scope of the direct decarboxylative amidosulfonation (DDAS) platform is enabled by the efficient direct conversion of carboxylic acids to sulfinic acids that are catalyzed by acridine photocatalysts and interfaced with copper-catalyzed sulfur-nitrogen bond-forming cross-couplings with both electrophilic and nucleophilic reagents.

Recommanded Product: 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. This gave the compound its name. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Other examples are the fire ant toxin solenopsin, the nicotine analog anabasine of tree tobacco (Nicotiana glauca), lobeline of Indian tobacco. Application of C5H11NO.

Nara, Susheel J.;Jogi, Srinivas;Cheruku, Srinivas;Kandhasamy, Sarkunam;Jaipuri, Firoz;Kathi, Pavan Kalyan;Reddy, Subba;Sarodaya, Sanket;Cook, Erica M.;Wang, Tao;Sitkoff, Doree;Rossi, Karen A.;Ruzanov, Max;Kiefer, Susan E.;Khan, Javed A.;Gao, Mian;Reddy, Satyanarayana;Sivaprasad LVJ, Sankara;Sane, Ramola;Mosure, Kathy;Zhuo, Xiaoliang;Cao, Gary G.;Ziegler, Milinda;Azzara, Anthony;Krupinski, John;Soars, Matthew G.;Ellsworth, Bruce A.;Wacker, Dean A. research published 《 Discovery of BMS-986339, a Pharmacologically Differentiated Farnesoid X Receptor Agonist for the Treatment of Nonalcoholic Steatohepatitis》, the research content is summarized as follows. While several farnesoid X receptor (FXR) agonists under clin. investigation for the treatment of nonalcoholic steatohepatitis (NASH) have shown beneficial effects, adverse effects such as pruritus and elevation of plasma lipids have limited their clin. efficacy and approvability. Herein, we report the discovery and preclin. evaluation of compound 32 (BMS-986339), a nonbile acid FXR agonist with a pharmacol. distinct profile relative to our previously reported agonist BMS-986318. Compound 32 exhibited potent in vitro and in vivo activation of FXR, albeit with a context-dependent profile that resulted in tissue-selective effects in vivo. To our knowledge, this is the first report that demonstrates differential induction of Fgf15 in the liver and ileum by FXR agonists in vivo. Compound 32 demonstrated robust antifibrotic efficacy despite reduced activation of certain genes in the liver, suggesting that the addnl. pharmacol. of BMS-986318 does not further benefit efficacy, possibly presenting an opportunity for reduced adverse effects. Further evaluation in humans is warranted to validate this hypothesis.

Application of C5H11NO, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst: C5H5N + 3 H2 → C5H10NH. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol. SDS of cas: 5382-16-1.

Nagare, Yadav Kacharu;Shah, Imtiyaz Ahmad;Yadav, Jyothi;Pawar, Amol Prakash;Choudhary, Rahul;Chauhan, Pankaj;Kumar, Indresh research published 《 Electrochemical Oxidative Coupling Between Benzylic C(sp³)-H and N-H of Secondary Amines: Rapid Synthesis of α-Amino α-Aryl Esters》, the research content is summarized as follows. An intermol. electrochem. coupling between the benzylic C(sp³)-H bond and various secondary amines is reported. The electronic behavior of two electronically rich units viz the α-position of α-aryl acetates and amines was engineered electrochem., thus facilitating their reactivity for the direct access of α-amino esters. A series of acyclic/cyclic secondary amines and α-aryl acetates were tested to furnish the corresponding α-amino esters with high yields (up to 92%) under mild conditions.

SDS of cas: 5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. It is a colorless liquid with an odor described as objectionable, and typical of amines. Category: piperidines.

Murthy, Vallabhaneni S.;Tamboli, Yasinalli;Krishna, Vagolu Siva;Sriram, Dharmarajan;Akber Ansari, Siddique;Alarfaj, Abdullah A.;Hirad, Abdurahman H.;Vijayakumar, Vijayaparthasarathi research published 《 Design and characterisation of piperazine-benzofuran integrated dinitrobenzenesulfonamide as Mycobacterium tuberculosis H37Rv strain inhibitors》, the research content is summarized as follows. Mol. hybridization of four bioactive fragments piperazine, substituted-benzofuran, amino acids, and 2,4-dinitrobenzenesulfonamide as single mol. architecture was designed. A series of new hybrids were synthesized and subjected to evaluation for their inhibitory activity against Mycobacterium tuberculosis (Mtb) H37Rv. A number were found to exhibit MIC as 1.56μg/mL, equally active as ethambutol whereas 4a, 4c, 4j (I–III, resp.) displayed MIC 0.78μg/mL and were superior to ethambutol. Tested compounds demonstrated an excellent safety profile with very low toxicity, good selectivity index, and antioxidant properties. All the newly synthesized compounds were thoroughly characterized by anal. methods. The result was further supported by mol. modeling studies on the crystal structure of Mycobacterium tuberculosis enoyl reductase.

Category: piperidines, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem