Li, Tiantian team published research on Science of the Total Environment in 2020 | 2403-88-5

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol.

Li, Tiantian;Huang, Yu;Wei, Gaoliang;Zhang, Ya-nan;Zhao, Yuanhui;Crittenden, John C.;Li, Chao research published 《 Quantitative structure-activity relationship models for predicting singlet oxygen reaction rate constants of dissociating organic compounds》, the research content is summarized as follows. As singlet oxygen (1O2) is ubiquitous in the environment, 1O2-involved oxidation may play an important role in the transformation and fate of organic pollutants. Accordingly, the reaction rate constants (k1O2) of organic compounds with 1O2 are important to determine the environmental fate and persistence assessment of organic pollutants. However, currently there are limited k1O2 data available, especially for organic chems. with different charged (deprotonated/protonated) forms. Herein three quant. structure-activity relationship (QSAR) models (one comprehensive model and two models for neutral and deprotonated mols.) were created for predicting aqueous k1O2 values for diversely dissociating mols. The models include larger datasets (180 chems.) and have wider applicability domain than previous ones. Mol. structural characteristics (only half-wave potential is present in both models) determining the 1O2 reaction rate of neutral and deprotonated mols. vary greatly. The comparison results of predicting k1O2 values of organic compounds at certain pH conditions show that the combination of the QSAR models for neutral and deprotonated mols. has advantages over the comprehensive QSAR model. This work is the first study to predict k1O2 for a wide variety of neutral and deprotonated mols. and provides an important tool for assessing the fate of organic pollutants in aquatic environments.

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Li, Shunyao team published research on Organic & Biomolecular Chemistry in 2021 | 84358-13-4

Reference of 84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Reference of 84358-13-4.

Li, Shunyao;Zhang, Lanfei;He, Qian;Zhang, Xiaofei;Yang, Chunhao research published 《 Synthesis of 2-alkyl-chroman-4-ones via cascade alkylation-dechlorination of 3-chlorochromones》, the research content is summarized as follows. An efficient and mild synthetic approach for 2-alkyl-substituted chroman-4-ones via zinc-mediated cascade decarboxylative β-alkylation and dechlorination of 3-chlorochromones was developed. This transformation employed com. available starting materials and was performed under mild conditions without heat, visible light, peroxide or heavy metals. Moreover, various alkyl NHPI esters with functional groups and differently substituted 3-chlorochromones were tolerated, affording the targeted products with moderate to excellent yields. This protocol could be utilized to construct a diverse library of 2-substituted chroman-4-one derivatives, which could be useful in the discovery of lead compounds for drug discovery in the future.

Reference of 84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Li, Qianqian team published research on Environmental Science & Technology in 2018 | 2403-88-5

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. It is a colorless liquid with an odor described as objectionable, and typical of amines. Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol.

Li, Qianqian;Huang, Xinchen;Su, Guijin;Zheng, Minghui;Huang, Chunhua;Wang, Mengjing;Ma, Chunyan;Wei, Da research published 《 The Regular/Persistent Free Radicals and Associated Reaction Mechanism for the Degradation of 1,2,4-Trichlorobenzene over Different MnO2 Polymorphs》, the research content is summarized as follows. The role of regular/persistent free radicals on the catalytic activity of K+-tuned MnO2 tunnel structures is poorly understood to date. Herein, three MnO2 polymorphs (α-, β-, and δ-MnO2) were synthesized and examined toward the degradation of 1,2,4-trichlorobenzene (1,2,4-TrCBz) at 300 °C. δ-MnO2, with a two-dimensional-layered tunnel structure tuned by K+, exhibited the highest activity among the three MnO2 polymorphs. The ESR spectroscopy results confirmed that δ-MnO2 featured the most abundant reactive oxygen species (ROS: O2-•, •OH, and 1O2), followed by α-MnO2 (O2-• and 1O2), and β-MnO2 (O2-•), being supported by the calculated energy barrier. It was, intriguingly, noted that persistent organic free radicals, newly recognized as emerging surface-stabilized compound, were remarkably detected in α- and β-MnO2/1,2,4-TrCBz systems but not in more reactive δ-MnO2/1,2,4-TrCBz system. These might contribute to discrepant oxidative degradation process. During the oxidative process, intermediates, including benzoic acid and glycerol, formed via attack by ROS. Upon further attack, these intermediates fragmented into smaller mols. such as formic, acetic, propionic, and butyric acids. The present findings give deeper insights into the role of free radicals on the catalytic degradation of chlorinated aromatics

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Li, Jiacheng team published research on Journal of Medicinal Chemistry in | 84358-13-4

84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., Name: 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid

Piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. This gave the compound its name. 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. Other examples are the fire ant toxin solenopsin, the nicotine analog anabasine of tree tobacco (Nicotiana glauca), lobeline of Indian tobacco. Name: 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid.

Li, Jiacheng;Liu, Ting;Song, Yuanli;Wang, Mingyu;Liu, Liping;Zhu, Hongwen;Li, Qi;Lin, Jin;Jiang, Hualiang;Chen, Kaixian;Zhao, Kehao;Wang, Mingliang;Zhou, Hu;Lin, Hua;Luo, Cheng research published 《 Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer》, the research content is summarized as follows. Aberrant hyperactivation of cyclins results in carcinogenesis and therapy resistance in cancers. Direct degradation of the specific cyclin or cyclin-dependent kinase (CDK)-cyclin complex by small-mol. degraders remains a great challenge. Here, we applied the first application of hydrophobic tagging to induce degradation of CDK9-cyclin T1 heterodimer, which is required to keep productive transcription of oncogenes in cancers. LL-K9-3 (I) was identified as a potent small-mol. degrader of CDK9-cyclin T1. Quant. and time-resolved proteome profiling exhibited LL-K9-3-induced selective and synchronous degradation of CDK9 and cyclin T1. The expressions of androgen receptor (AR) and cMyc were reduced by LL-K9-3 (I) in 22RV1 cells. LL-K9-3 (I) exhibited enhanced anti-proliferative and pro-apoptotic effects compared with its parental CDK9 inhibitor SNS032 and suppressed downstream signaling of CDK9 and AR more effectively than SNS032. Moreover, LL-K9-3 (I) inhibited AR and Myc-driven oncogenic transcriptional programs and exerted stronger inhibitory effects on several intrinsic target genes of AR than the monomeric CDK9 PROTAC (Thal-SNS032).

84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., Name: 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Li, Jia team published research on Frontiers in Chemistry (Lausanne, Switzerland) in 2022 | 5382-16-1

Name: 4-Piperidinol, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. It is a colorless liquid with an odor described as objectionable, and typical of amines. Name: 4-Piperidinol.

Li, Jia;Li, Yu-An;Wu, Ge;Zhang, Xu research published 《 Metal-free aminohalogenation of quinones with alkylamines and NXS at room temperature》, the research content is summarized as follows. A simple and practical strategy for intermol. aminohalogenation of quinone with alkyl amines and NXS was developed for preparation of halo(amino)naphthalenediones I [X = H, Cl, Br, I; R1 = Me; R2 = 2-cyanoethyl, (4-bromophenyl)methyl, phenethyl, (3S)-3-(2-methylphenoxy)-3-phenyl-propyl; R1 = R2 = (CH2)2O(CH2)2, (CH2)2CH(OH)(CH2)2, (CH2)2CH(CO2Me)(CH2)2], in which haloamines generated in situ were employed as bifunctional reagents. The reaction system was reliable, efficient and wide in substrate range, which was suitable for the two-fold aminochlorination of 1, 4-benzoquinones, large-scale reaction and late-stage modification of pharmaceuticals.

Name: 4-Piperidinol, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Li, Hongdan team published research on Talanta in 2021 | 2403-88-5

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Name: 2,2,6,6-Tetramethyl-4-piperidinol

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Name: 2,2,6,6-Tetramethyl-4-piperidinol.

Li, Hongdan;Wang, Jiawei;Du, Jianxiu research published 《 A novel luminol chemiluminescence system induced by black phosphorus quantum dots for cobalt (II) detection》, the research content is summarized as follows. Black phosphorus quantum dots (BP QDs) were prepared through a solvothermal exfoliation method in alk. N-methyl-2-pyrrolidinone. The BP QDs induce distinct chemiluminescence (CL) of alk. luminol directly. A possible reaction mechanism is proposed by the study of CL spectrum, UV-visible absorption spectra, ESR spectra as well as radical scavenging experiments The presence of BP QDs significantly increases generation of active oxygen species, which oxidize luminol and lead to intense CL emission at 425 nm. The reaction of luminol with BP QDs are specifically catalyzed by cobalt (II) ion, this presents a sensitive CL method for cobalt (II) ion. A linear response range extends from 2.5 to 2000.0 pmol/L cobalt (II) ion and a detection limit of 0.7 pmol/L (3sb) is acquired. The method displays a good precision approved by a relative standard deviation of 1.9% at 100.0 pmol/L cobalt (II) ion solution (n = 11). A preliminary application of the method was conducted by successful determination of cobalt amount in silica gel and rain water samples.

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Name: 2,2,6,6-Tetramethyl-4-piperidinol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Li, Chen-Xuan team published research on Chemical Engineering Journal (Amsterdam, Netherlands) in 2019 | 2403-88-5

Related Products of 2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. It is a colorless liquid with an odor described as objectionable, and typical of amines. Related Products of 2403-88-5.

Li, Chen-Xuan;Chen, Chang-Bin;Wang, Yun-Jie;Fu, Xian-Zhong;Cui, Shuo;Lu, Jia-Yuan;Li, Jie;Liu, Hou-Qi;Li, Wen-Wei;Lau, Tai-Chu research published 《 Insights on the pH-dependent roles of peroxymonosulfate and chlorine ions in phenol oxidative transformation》, the research content is summarized as follows. The formation of halogenated disinfection byproducts (DBPs) during organic pollutants degradation in advanced oxidation processes (AOPs) has raised growing concerns globally. However, the detailed roles of chlorine ions (Cl) in pollutant degradation by peroxymonosulfate (PMS) alone remain controversial so far. Here, we shed light on the PMS-Cl-phenol interactions and revealed a previously overlooked pH-dependent phenol transformation pathway. At acidic pH, Cl significantly accelerated the phenol removal. The Cl-PMS reaction resulted in abundant reactive chlorine species, which attacked phenol to form 4-chlorophenol and 2, 4-dichlorophenol as the main transformation products. In contrast, the impact of Cl became negligible at alk. pH. Raising the pH severely suppressed the phenol chlorination and significantly stimulated generation of singlet oxygen (1O2) for degradation of phenol and the minor formed chlorophenols. The 1O2 was resulted from a combined effect of PMS self-decomposition and PMS-benzoquinone interaction at alk. pH. Our results imply a previously-underestimated impact of Cl on phenolic compounds degradation in PMS-based AOPs and underscore a potential risk of chlorinated DBPs formation under environmental conditions.

Related Products of 2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Li, Chenxu team published research on Chemical Engineering Journal (Amsterdam, Netherlands) in 2019 | 2403-88-5

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Electric Literature of 2403-88-5

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Electric Literature of 2403-88-5.

Li, Chenxu;Wu, Jiaen;Peng, Wei;Fang, Zhendong;Liu, Jie research published 《 Peroxymonosulfate activation for efficient sulfamethoxazole degradation by Fe3O4/β-FeOOH nanocomposites: Coexistence of radical and non-radical reactions》, the research content is summarized as follows. Environmental friendly magnetic Fe3O4/β-FeOOH nanocomposites with low cost were prepared via a simple one pot method and their physiochem. properties were investigated. The Fe3O4/β-FeOOH nanocomposites efficiently catalyzed the activation of peroxymonosulfate (PMS) for sulfamethoxazole (SMX) degradation and can be easily recovered through magnetic separation The effects of catalyst dosage, PMS dosage, temperature and pH were evaluated. The catalyst showed great stability and reusability based on the successive degradation cycles. The reactive oxygen species (ROS) including sulfate radical (SO4), hydroxyl radical (·OH) and singlet oxygen (1O2) were generated in the Fe3O4/β-FeOOH/PMS system, while both of SO4 and 1O2 were dominantly attributed to the SMX degradation The special tunnel-type structure and surface oxygen vacancies of β-FeOOH may be responsible for the high catalytic activity towards PMS to degrade SMX. At last, the catalytic mechanism of PMS on the surface of catalysts were proposed.

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Electric Literature of 2403-88-5

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Lee, Yeon Hee team published research on ACS Medicinal Chemistry Letters in 2021 | 5382-16-1

5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., SDS of cas: 5382-16-1

Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. SDS of cas: 5382-16-1.

Lee, Yeon Hee;Cha, Hyeon-Min;Hwang, Jun Yeon;Park, So Yeong;Vishakantegowda, Avinash G.;Imran, Ali;Lee, Joo-Youn;Yi, Yoon-Sun;Jun, Sangmi;Kim, Ga Hyeon;Kang, Hyo Jin;Chung, Sang J.;Kim, Meehyein;Kim, Hyejin;Han, Soo Bong research published 《 Sulfamoylbenzamide-based Capsid Assembly Modulators for Selective Inhibition of Hepatitis B Viral Replication》, the research content is summarized as follows. As the spread of infections caused by hepatitis B virus (HBV) threatens public health worldwide, investigations from multiple perspectives and of various mechanisms of action are urgently required to increase the HBV cure rate. Targeting the encapsidation of the nuclear capsid protein (core protein, HBc) has emerged as an attractive strategy for inhibiting the viral assembly process; however, a drug targeting this mechanism has not yet been approved. We synthesized novel sulfamoylbenzamides (SBAs) as capsid assembly modulators of HBV and found that the effects and safety profiles of compounds 3 (I) and 8 (II) have potential therapeutic applicability against HBV. The formation of tubular particles was time-dependent in the presence of 3 (I), indicating a new mode of protein assembly by SBA compounds Our findings provide a new entity for developing safe and efficient treatments for HBV infection.

5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., SDS of cas: 5382-16-1

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Lau, Mei-Tung team published research on Polymer in 2022 | 2403-88-5

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. It is a colorless liquid with an odor described as objectionable, and typical of amines. Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol.

Lau, Mei-Tung;Li, Zikang;Sun, Zelin;Wong, Wai-Yeung research published 《 Synthesis, characterization and thermoelectric properties of new non-conjugated nitroxide radical-containing metallopolymers》, the research content is summarized as follows. In the last decade, there is an intense interest in the study of conjugated organic polymers for thermoelec. (TE) application. Non-conjugated polymers are usually considered as the insulators with no or extremely low elec. conductivity Nevertheless, non-conjugated radical polymers (NCRPs) are different from those polymers in which they can be widely applied in electronic technol., for example, as battery electrode materials, conductors in solid-state and memory devices, but they have not been used for the TE application. Here, three metal-containing NCRPs P1-P3 with different nitroxide radical moieties were synthesized and coated with single-walled carbon nanotubes (SWCNTs) to form various polymer composites. P2 exhibited the highest elec. conductivity of 1310.0 ± 3.92 S m-1 when the SWCNT content reached 60%. P3 had the highest Seebeck coefficient of 62.5 ± 0.40μV K-1 when the SWCNT ratio reached 90%. The highest power factor of 130.1 ± 1.61μW m-1 K-2 was achieved from the P3/SWCNT composite at the mass ratio of 90%. The results showed that the NCRPs could be one of the potential TE materials of further study.

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem