Properties and Exciting Facts About N-(2-Aminoethyl)piperidine

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Imine Analogues of Tricyclic Antidepressants

Analogues of tricyclic antidepressants were synthesized in which the alpha-carbon of the side chain was replaced by nitrogen.The antidepressant activity of these imines, as measured by the reversal of the effects of tetrabenazine in mice, showed a structure-activity relationship similar to that of the carbon analogues.The most active imine (19) was six times as potent as amitriptyline.Some of the compounds differed from amitriptyline in that they produced stimulation in mice.

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Piperidine – Wikipedia,
Piperidine | C5H4659N – PubChem

 

Extracurricular laboratory:new discovery of 27578-60-5

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Synthesis, crystal structures, and biological activity of schiff base zinc(II) complexes derived from (2-piperidin-1-ylethyl)-(1-pyridin-2- ylethylidene)amine

Two new similar zinc(II) complexes, [ZnI2L] (1) and [Zn(NCS)2L] (2), derived from the Schiff base (2-piperidin-1-ylethyl) -(1-pyridin-2-ylethylidene)amine(L), were prepared and structurally characterized by X-ray diffraction. The Zn atom in each complex is five-coordinated by the three N atoms of the Schiff base ligand, and by two I or N atoms of the terminal iodide or thiocyanate groups, forming distorted square-pyramidal coordination. The urease inhibitory activities of the complexes and the ligand were evaluated. Copyright Taylor & Francis Group, LLC.

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Piperidine – Wikipedia,
Piperidine | C5H4084N – PubChem

 

Discovery of tert-Butyl 3-oxo-2,3-dihydrospiro[indene-1,4′-piperidine]-1′-carboxylate

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Synthesis and SAR of substituted tetrahydrocarbazole derivatives as new NPY-1 antagonists

The SAR of a new series of tetrahydrocarbazole derivatives is described: the appropriate decoration of this template led to the identification of a new class of NPY-1 antagonists showing good in vitro potency and a promising in vivo pharmacokinetic profile in rat.

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Piperidine – Wikipedia,
Piperidine | C5H23106N – PubChem

 

The important role of 41979-39-9

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ARYLAMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

The present invention relates to arylamide derivatives having dual pharmacological activity towards both the alpha2delta subunit, in particular the alpha2delta-1 subunit,of the voltage-gated calcium channel and the mu-opioid receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.

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Piperidine – Wikipedia,
Piperidine | C5H5832N – PubChem

 

Properties and Exciting Facts About (R)-tert-Butyl 3-hydroxypiperidine-1-carboxylate

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 143900-43-0, help many people in the next few years.Formula: C10H19NO3

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UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF

Disclosed herein, inter alia, compounds and methods of use thereof for the modulation of USP7 activity.

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Piperidine – Wikipedia,
Piperidine | C5H14684N – PubChem

 

Properties and Exciting Facts About 19125-34-9

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, SDS of cas: 19125-34-9, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 19125-34-9, Name is N-Phenylpiperidin-4-one, molecular formula is C11H13NO. In a Patent, authors is £¬once mentioned of 19125-34-9

Compounds useful as reversible inhibitors of cysteine proteases

Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formulas (I), (II), (Ia) and (Ib) further defined herein. The compounds are useful for treating autoimmune diseases. Also disclosed are processes for making such novel compounds. 1

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Piperidine – Wikipedia,
Piperidine | C5H10487N – PubChem

 

The important role of 4-Amino-1-benzylpiperidine

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Related Products of 50541-93-0, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 50541-93-0, Name is 4-Amino-1-benzylpiperidine, molecular formula is C12H18N2. In a Patent£¬once mentioned of 50541-93-0

6-BENZIMIDAZOLYL-2-MORPHOLINO-4- (AZETIDINE, PYRROLIDINE, PIPERIDINE OR AZEPINE) PYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS

The invention concerns pyrimidine derivatives of Formula (I): wherein each of p, R1, R2, q, R3, r, R4, s, t, X1 and Q1 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in a method for producing an anti-proliferative effect in a warm blooded animal such as man

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Piperidine – Wikipedia,
Piperidine | C5H12385N – PubChem

 

Simple exploration of 162167-97-7

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2? Biaryl amides as novel and subtype selective M1 agonists. Part I: Identification, synthesis, and initial SAR

Biaryl amides were discovered as novel and subtype selective M1 muscarinic acetylcholine receptor agonists. The identification, synthesis, and initial structure-activity relationships that led to compounds 3j and 4c, possessing good M1 agonist potency and intrinsic activity, and subtype selectivity for M1 over M2-5, are described.

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Piperidine – Wikipedia,
Piperidine | C5H17120N – PubChem

 

Awesome and Easy Science Experiments about 5472-49-1

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SUBSTITUTED PIPERAZINES, (1,4) DIASZEPINES, AND 2,5-DIAZABICYCLO (2.2.1) HEPTANES AS HISTAMINE H1 AND/OR H3 ANTAGONISTS OR HISTAMINE H3 REVERSE ANTAGONISTS

The present invention relates to novel piperazine and azepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurodegenerative disorders including Alzheimer’s disease.

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Piperidine – Wikipedia,
Piperidine | C5H13183N – PubChem

 

The Absolute Best Science Experiment for 29976-53-2

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Recommanded Product: N-Carbethoxy-4-piperidone, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 29976-53-2, Name is N-Carbethoxy-4-piperidone, molecular formula is C8H13NO3. In a Article, authors is Bridoux, Alexandre£¬once mentioned of 29976-53-2

Synthesis of 8-substituted tetrahydro-gamma-carbolines

The Fischer reaction is applied to the synthesis of 8-substituted tetrahydro-gamma-carbolines with electron-donating or electron-withdrawing groups, using catalytic or thermal methods. The reaction conditions must be varied according to the nature of the N 1 substituent of the piperidone. The best results are observed when a releasing group is present on the arylhydrazine and a benzyl substituent on the nitrogen of piperidone. Formation of carbolines with a withdrawing substituent is observed in soft acidic conditions; in others, reaction ended at the hydrazone level or did not evolve.

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Piperidine – Wikipedia,
Piperidine | C5H10007N – PubChem