Reference of 5472-49-1, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.5472-49-1, Name is 1-(3-Chloropropyl)piperidine hydrochloride, molecular formula is C8H17Cl2N. In a Article,once mentioned of 5472-49-1
The therapy of complex neurodegenerative diseases requires the development of multitarget-directed drugs (MTDs). Novel indole derivatives with inhibitory activity towards acetyl/butyrylcholinesterases and monoamine oxidases A/B as well as the histamine H3 receptor (H3R) were obtained by optimization of the neuroprotectant ASS234 by incorporating generally accepted H3R pharmacophore motifs. These small-molecule hits demonstrated balanced activities at the targets, mostly in the nanomolar concentration range. Additional in vitro studies showed antioxidative neuroprotective effects as well as the ability to penetrate the blood?brain barrier. With this promising in vitro profile, contilisant (at 1 mg kg?1 i.p.) also significantly improved lipopolysaccharide-induced cognitive deficits.
The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 5472-49-1 is helpful to your research. Reference of 5472-49-1
Reference:
Piperidine – Wikipedia,
Piperidine | C5H13177N – PubChem