A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, HPLC of Formula: C12H13FN2O, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 84163-77-9, Name is 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole, molecular formula is C12H13FN2O. In a Article, authors is Fu, Wei,once mentioned of 84163-77-9
Schizophrenia is a chronic, disabling mental disorder that affects about one percent of world’s population. Drugs acting on multiple targets have been demonstrated to provide superior efficacy in schizophrenia than agents acting on single target. In this study, based on FW01, a selective potent 5-HT1A receptor agonist discovered via dynamic pharmacophore-based virtual screening, molecular hybridization strategy was employed to optimize its in vitro activity over D2 and 5-HT2A receptors. The optimized compound 9f was found to show dual potent D2 and 5-HT2A receptors antagonistic activity. In addition, compound 9f showed good in vivo metabolic stability with t1/2 of 2 h in ICR mice and good capability to penetrate the blood-brain barrier with Kp value of 4.03. These results demonstrated that the dual D2 and 5-HT1A receptor antagonist 9f could serve as a promising lead compound to discover potent antipsychotic agents.
Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about is helpful to your research. HPLC of Formula: C12H13FN2O
Reference:
Piperidine – Wikipedia,
Piperidine | C5H17798N – PubChem