Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Computed Properties of C7H15Cl2N, Which mentioned a new discovery about 2008-75-5
Four novel 4-(1H-imidazo[4,5-f]-1,10-phenanthrolin-2-yl)phenol derivatives 1-4 have been synthesized, and their G-quadruplex DNA-binding interactions, telomerase inhibition, antiproliferative activity, cell cycle arrest, and apoptotic induction were studied. All compounds show the preferential h-telo, c-myc, and c-kit2 G-quadruplex binding affinity and the G-quadruplex versus duplex selectivity. In the case of the same G-quadruplex target, the compound 1 exhibits better stabilization effect (DeltaTm) than the other three compounds and also gives 80.2% inhibition of telomerase activity at 7.5 muM. All compounds can promote selectively the formation of parallel G-quadruplex structure of both c-myc and c-kit2 without addition of any cations. Four compounds display the cytotoxicity activities against HeLa and HepG2 cells by MTT assay with IC50 values of about 10-6 and 10 -5 M, respectively, and cause a substantial decrease in the G 2/M-phase cell population and a significant increase in the number of apoptotic cells.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Computed Properties of C7H15Cl2N, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 2008-75-5
Reference：
Piperidine – Wikipedia,
Piperidine | C5H11283N – PubChem