Electric Literature of 24228-40-8, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.24228-40-8, Name is Ethyl N-benzylpiperidine-4-carboxylate, molecular formula is C15H21NO2. In a Article，once mentioned of 24228-40-8
We report our successful effort to increase the PDE3 selectivity of PDE10A inhibitor pyridyl cinnoline 1 using a combination of computational modeling and structural-activity relationship investigations. An analysis of the PDE3 catalytic domain compared to the co-crystal structure of cinnoline analog 1 in PDE10A revealed two areas of structural differences in the active sites and suggested areas on the scaffold that could be modified to exploit those unique structural features. Once SAR established the cinnoline as the optimal scaffold, modifications on the methoxy groups of the cinnoline and the methyl group on the pyridine led to the discovery of compounds 33 and 36. Both compounds achieved significant improvement in selectivity against PDE3 while maintaining their PDE10A inhibitory activity and in vivo metabolic stability comparable to 1.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Electric Literature of 24228-40-8, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 24228-40-8
Reference：
Piperidine – Wikipedia,
Piperidine | C5H20615N – PubChem